Versatile Fluorescent Conjugated Polyelectrolyte-Capped Mesoporous Silica Nanoparticles for Controlled Drug Delivery and Imaging
文献类型：期刊论文
| 作者 | Pu F ; Liu X ; Yang XJ ; Liu Z ; Ren JS ; Wang S ; Qu XG |
| 刊名 | chempluschem
 |
| 出版日期 | 2013 |
| 卷号 | 78期号:7页码:656-662 |
| 关键词 | RESPONSIVE CONTROLLED-RELEASE POLYMERS MOLECULES SYSTEM DNA NANOSPHERE NANOVALVES SURFACES MICELLES CARRIERS |
| ISSN号 | 2192-6506 |
| 通讯作者 | ren js |
| 中文摘要 | fluorescent conjugated polyelectrolytes (cpes) with a large extinction coefficient, high quantum efficiency, good photostability, and efficient intramolecular/intermolecular exciton migration have recently received great research attention as a new generation of fluorescent probes. herein, the unique properties of fluorescent conjugated polyelectrolyte and mesoporous silica nanoparticles (msns) are combined to prepare a ph-sensitive drug delivery and cellular imaging system using a simple and more general method. to the best of our knowledge, this is the first proof-of-concept investigation on the use of fluorescent conjugated polyelectrolyte as both the capping agent of msns and the cellular imaging probe in parallel. moreover, the bifunctional nanomaterial exhibits low cytotoxicity and good biocompatibility demonstrated by a cytotoxicity assay against hepg2 cells and a hemolysis assay against human red-blood cells. it is a promising candidate for simultaneous diagnostics and therapeutics and can also provide a general strategy to develop novel multifunctional nanomedical systems. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000321430900013 |
| 公开日期 | 2014-04-20 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/50474]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Pu F,Liu X,Yang XJ,et al. Versatile Fluorescent Conjugated Polyelectrolyte-Capped Mesoporous Silica Nanoparticles for Controlled Drug Delivery and Imaging[J]. chempluschem,2013,78(7):656-662. |
| APA | Pu F.,Liu X.,Yang XJ.,Liu Z.,Ren JS.,...&Qu XG.(2013).Versatile Fluorescent Conjugated Polyelectrolyte-Capped Mesoporous Silica Nanoparticles for Controlled Drug Delivery and Imaging.chempluschem,78(7),656-662. |
| MLA | Pu F,et al."Versatile Fluorescent Conjugated Polyelectrolyte-Capped Mesoporous Silica Nanoparticles for Controlled Drug Delivery and Imaging".chempluschem 78.7(2013):656-662. |
入库方式： OAI收割
来源：长春应用化学研究所
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