Recent Progress on Molecular Recognition and Modulation of Nucleic Acids Using Chiral Rare-Earth Complexes
文献类型：期刊论文
| 作者 | Zhao CQ ; Qu XG |
| 刊名 | progress in chemistry
 |
| 出版日期 | 2013 |
| 卷号 | 25期号:4页码:539-544 |
| 关键词 | CATIONIC LANTHANIDE COMPLEXES G-QUADRUPLEX FORMATION HUMAN TELOMERIC DNA BINDING SELECTIVITY PROBES LUMINESCENCE TRANSITION ENANTIOMER CLEAVAGE |
| ISSN号 | 1005-281x |
| 通讯作者 | qu xg |
| 中文摘要 | there is great interest in design and synthesis of small molecules which selectively target specific genes to inhibit biological functions. among these studies, chiral dna recognition has been received much attention because more evidences have shown that conversions of the chirality and diverse conformations of dna are involved in a series of important life events. in addition, chiral molecular recognition of dna is important for rational drug design and developing structural probes of dna conformation. over the past few decades, considerable attention has focused on the design of dna binding chiral agents, especially b-dna, z-dna and g-quadruplex dna binding agents. rare-earth compounds, due to a unique 4f(n) electronic configuration, have been widely used as probes in luminescent resonance energy transfer for bioassays and as reagents for diagnosis in magnetic resonance imaging. as chemical nucleases, rare-earth complexes have also shown a high efficiency to hydrolyze dna and rna without redox chemistry. recently, there is great interest in the design and synthesis of chiral rare-earth complexes which selectively target specific dna. excitedly, some interesting results have been reported. this review summarizes the current progress in chiral rare-earth complexes binding to nucleic acids and their chiral selectivity. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 中文 |
| WOS记录号 | WOS:000318131600012 |
| 公开日期 | 2014-04-20 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/50483]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Zhao CQ,Qu XG. Recent Progress on Molecular Recognition and Modulation of Nucleic Acids Using Chiral Rare-Earth Complexes[J]. progress in chemistry,2013,25(4):539-544. |
| APA | Zhao CQ,&Qu XG.(2013).Recent Progress on Molecular Recognition and Modulation of Nucleic Acids Using Chiral Rare-Earth Complexes.progress in chemistry,25(4),539-544. |
| MLA | Zhao CQ,et al."Recent Progress on Molecular Recognition and Modulation of Nucleic Acids Using Chiral Rare-Earth Complexes".progress in chemistry 25.4(2013):539-544. |
入库方式： OAI收割
来源：长春应用化学研究所
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