Synthesis, characterization and adsorption performance of molecularly imprinted nanoparticles for tripterine by precipitation polymerization
文献类型：期刊论文
| 作者 | Liu, Yuan2,3; Zhang, Guifeng2; Deng, Lihong1; Lei, Jiandu1; Wang, Lianyan2; He, Jing1 |
| 刊名 | ANALYTICAL METHODS
 |
| 出版日期 | 2014 |
| 卷号 | 6期号:3页码:684-689 |
| 关键词 | liquid-chromatography down-regulation leukemia-cells celastrol apoptosis separation triterpene inhibitor arthritis mice |
| ISSN号 | 1759-9660 |
| 其他题名 | Anal. Methods |
| 中文摘要 | Synthesis of molecularly imprinted nanoparticles for tripterine with good selectivity and high adsorption capacity by precipitation polymerization is presented for the first time, in which tripterine, methacrylic acid and ethylene glycol dimethacrylate were used as a template molecule, functional monomer and cross-linker, respectively. The preparation conditions of molecularly imprinted nanoparticles were optimized, and the optimal molar ratio of template to functional monomer to cross-linker was 1 : 3 : 3. And non-imprinted polymers (NIPs) for control experiments were also prepared. The nanoparticles were characterized using a scanning electron microscope, laser particle size analyzer and BET, respectively. The results indicated that the imprinted nanoparticles were spherical in shape and the size was relatively uniform. Selectivity analysis suggested that the obtained imprinted nanoparticles could specifically recognize tripterine. In addition, adsorption kinetics and adsorption isotherm of the imprinted nanoparticles were utilized to study the binding characteristics of the imprinted nanoparticles. The results revealed that the imprinted nanoparticles had high adsorption capacity and the maximum adsorption capacity of tripterine on the imprinted particles was up to 145.97 mg g(-1). In potential application research, this adsorbent was satisfactorily employed as a solid-phase extraction sorbent to extract TTR in urine samples. |
| 英文摘要 | Synthesis of molecularly imprinted nanoparticles for tripterine with good selectivity and high adsorption capacity by precipitation polymerization is presented for the first time, in which tripterine, methacrylic acid and ethylene glycol dimethacrylate were used as a template molecule, functional monomer and cross-linker, respectively. The preparation conditions of molecularly imprinted nanoparticles were optimized, and the optimal molar ratio of template to functional monomer to cross-linker was 1 : 3 : 3. And non-imprinted polymers (NIPs) for control experiments were also prepared. The nanoparticles were characterized using a scanning electron microscope, laser particle size analyzer and BET, respectively. The results indicated that the imprinted nanoparticles were spherical in shape and the size was relatively uniform. Selectivity analysis suggested that the obtained imprinted nanoparticles could specifically recognize tripterine. In addition, adsorption kinetics and adsorption isotherm of the imprinted nanoparticles were utilized to study the binding characteristics of the imprinted nanoparticles. The results revealed that the imprinted nanoparticles had high adsorption capacity and the maximum adsorption capacity of tripterine on the imprinted particles was up to 145.97 mg g(-1). In potential application research, this adsorbent was satisfactorily employed as a solid-phase extraction sorbent to extract TTR in urine samples. |
| WOS标题词 | Science & Technology ; Physical Sciences ; Life Sciences & Biomedicine ; Technology |
| 类目[WOS] | Chemistry, Analytical ; Food Science & Technology ; Spectroscopy |
| 研究领域[WOS] | Chemistry ; Food Science & Technology ; Spectroscopy |
| 关键词[WOS] | LIQUID-CHROMATOGRAPHY ; DOWN-REGULATION ; LEUKEMIA-CELLS ; CELASTROL ; APOPTOSIS ; SEPARATION ; TRITERPENE ; INHIBITOR ; ARTHRITIS ; MICE |
| 收录类别 | SCI |
| 原文出处 | |
| 语种 | 英语 |
| WOS记录号 | WOS:000330038500007 |
| 公开日期 | 2014-05-06 |
| 版本 | 出版稿 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/8226]  |
| 专题 | 过程工程研究所_研究所（批量导入） |
| 作者单位 | 1.Beijing Forestry Univ, Beijing Key Lab Lignocellulos Chem, Beijing 100083, Peoples R China 2.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Yuan,Zhang, Guifeng,Deng, Lihong,et al. Synthesis, characterization and adsorption performance of molecularly imprinted nanoparticles for tripterine by precipitation polymerization[J]. ANALYTICAL METHODS,2014,6(3):684-689. |
| APA | Liu, Yuan,Zhang, Guifeng,Deng, Lihong,Lei, Jiandu,Wang, Lianyan,&He, Jing.(2014).Synthesis, characterization and adsorption performance of molecularly imprinted nanoparticles for tripterine by precipitation polymerization.ANALYTICAL METHODS,6(3),684-689. |
| MLA | Liu, Yuan,et al."Synthesis, characterization and adsorption performance of molecularly imprinted nanoparticles for tripterine by precipitation polymerization".ANALYTICAL METHODS 6.3(2014):684-689. |
入库方式： OAI收割
来源：过程工程研究所
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