Optimization of Microwave-Assisted Extraction of Cordycepic Acid and Cordycepin from Cultured Cordyceps militaris by Response Surface Methodology
文献类型：期刊论文
| 作者 | Deng, Li1,2,3,4; Zhou, Tong-Yong1,2,3; Pi, Li1,2,3; Zhao, Xiao-Hui1,2,3; Han, Tao1,2,3; Li, Yi-Kang1,2,3; Han, Fa1,3 |
| 刊名 | asian journal of chemistry
 |
| 出版日期 | 2013-10-01 |
| 卷号 | 25期号:14页码:8065-8071 |
| 关键词 | Cordyceps militaris Cordycepin Cordycepic acid Microwave-assisted extraction Reponse surface methodology |
| ISSN号 | 0970-7077 |
| 通讯作者 | han, f (reprint author), chinese acad sci, northwest inst plateau biol, xining 810008, peoples r china. |
| 中文摘要 | the response surface methodology was employed to optimize the integrated extraction parameters of cordycepic acid and cordycepin from cultured cordyceps militaris (l.) link based on a single-factor experiment. the box-behnken design with three independent variables i.e., microwave power (w), water/material ratio (ml/g) and extraction time (min) was used. the experimental data obtained were fitted to a second-order polynomial equation using multiple regression analysis. the three-dimensional response surface plot and contour plot derived from the mathematical models were applied to determine the optimal conditions. the optimum extraction condition was obtained as follows: microwave-assisted extraction, microwave power of 649.33 w, extraction time of 5.74 min, water/material ratio of 38. 99 ml/g and extraction number of three. the yield of cordycepic acid and cordycepin were 2.47 and 0.79 %, respectively. under these conditions, the experimental values of 3.12 and 0.75 % well agreed with those predicted by the model. |
| 英文摘要 | the response surface methodology was employed to optimize the integrated extraction parameters of cordycepic acid and cordycepin from cultured cordyceps militaris (l.) link based on a single-factor experiment. the box-behnken design with three independent variables i.e., microwave power (w), water/material ratio (ml/g) and extraction time (min) was used. the experimental data obtained were fitted to a second-order polynomial equation using multiple regression analysis. the three-dimensional response surface plot and contour plot derived from the mathematical models were applied to determine the optimal conditions. the optimum extraction condition was obtained as follows: microwave-assisted extraction, microwave power of 649.33 w, extraction time of 5.74 min, water/material ratio of 38. 99 ml/g and extraction number of three. the yield of cordycepic acid and cordycepin were 2.47 and 0.79 %, respectively. under these conditions, the experimental values of 3.12 and 0.75 % well agreed with those predicted by the model. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, multidisciplinary |
| 研究领域[WOS] | chemistry |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000325096400094 |
| 公开日期 | 2014-05-09 |
| 源URL | [http://ir.nwipb.ac.cn/handle/363003/3917]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 作者单位 | 1.Chinese Acad Sci, Northwest Inst Plateau Biol, Xining 810008, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Adaptat & Evolut Plateau Biota, Xining 810008, Peoples R China 4.Chinese Acad Sci, Northwest Inst Plateau Biol, Huzhou Plateau Biol Resource Ctr Innovat, Huzhou 310001, Peoples R China |
| 推荐引用方式 GB/T 7714 | Deng, Li,Zhou, Tong-Yong,Pi, Li,et al. Optimization of Microwave-Assisted Extraction of Cordycepic Acid and Cordycepin from Cultured Cordyceps militaris by Response Surface Methodology[J]. asian journal of chemistry,2013,25(14):8065-8071. |
| APA | Deng, Li.,Zhou, Tong-Yong.,Pi, Li.,Zhao, Xiao-Hui.,Han, Tao.,...&Han, Fa.(2013).Optimization of Microwave-Assisted Extraction of Cordycepic Acid and Cordycepin from Cultured Cordyceps militaris by Response Surface Methodology.asian journal of chemistry,25(14),8065-8071. |
| MLA | Deng, Li,et al."Optimization of Microwave-Assisted Extraction of Cordycepic Acid and Cordycepin from Cultured Cordyceps militaris by Response Surface Methodology".asian journal of chemistry 25.14(2013):8065-8071. |
入库方式： OAI收割
来源：西北高原生物研究所
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