Structures of (1 -> 6)-beta-D-glucans from Bulgaria inquinans (Fries) and their immunological activities
文献类型：期刊论文
| 作者 | Bi, Hongtao1,2; Gao, Tingting1,2; Liu, Dongbo1; Tai, Guihua1; Wei, Min1; Zhou, Yifa1 |
| 刊名 | carbohydrate polymers
 |
| 出版日期 | 2013-04-02 |
| 卷号 | 93期号:2页码:547-552 |
| 关键词 | Bulgaria inquinans (Fries) Polysaccharide (1 -> 6)-beta-D-Glucan Lymphocyte proliferation |
| ISSN号 | 0144-8617 |
| 通讯作者 | wei, m (reprint author), ne normal univ, sch life sci, changchun 130022, peoples r china. |
| 中文摘要 | in previous study, an unbranched (1 -> 6)-beta-d-glucan with mw 2.6 kda was isolated from fruit bodies of bulgaria inquinans (fries). in present paper, three branched (1 -> 6)-beta-d-glucans were obtained from the water-extracted residues by a sequential koh-extraction, namely bik2, bik10 and bik30. their molecular weights were determined to be 37.5 kda (bik2), 288.9 kda (bik10) and 175.5 kda (bik30). structural analysis indicated that their backbones were substituted by single glucosyls at c-3 positions, the branching ratios were 0.01 (bik2), 0.17 (bik10), 0.25 (bik30). immunological tests showed that all the four beta-d-glucans could significantly increase the cona or lps-induced lymphocytes proliferation in vivo. moreover, branched (1 -> 6)-beta-d-glucans have more significantly lymphocytes proliferation activities than unbranched (1 -> 6)-beta-d-glucan, and the effect of (1 -> 6)-beta-d-glucans on lymphocytes proliferation increases along with molecular weights. the present results well enrich the structure-activity relationships of (1 -> 6)-beta-d-glucan, and indicate (1 -> 6)-beta-d-glucans from b. inquinans (fries) are potential immunostimulating agents. (c) 2012 elsevier ltd. all rights reserved. |
| 英文摘要 | in previous study, an unbranched (1 -> 6)-beta-d-glucan with mw 2.6 kda was isolated from fruit bodies of bulgaria inquinans (fries). in present paper, three branched (1 -> 6)-beta-d-glucans were obtained from the water-extracted residues by a sequential koh-extraction, namely bik2, bik10 and bik30. their molecular weights were determined to be 37.5 kda (bik2), 288.9 kda (bik10) and 175.5 kda (bik30). structural analysis indicated that their backbones were substituted by single glucosyls at c-3 positions, the branching ratios were 0.01 (bik2), 0.17 (bik10), 0.25 (bik30). immunological tests showed that all the four beta-d-glucans could significantly increase the cona or lps-induced lymphocytes proliferation in vivo. moreover, branched (1 -> 6)-beta-d-glucans have more significantly lymphocytes proliferation activities than unbranched (1 -> 6)-beta-d-glucan, and the effect of (1 -> 6)-beta-d-glucans on lymphocytes proliferation increases along with molecular weights. the present results well enrich the structure-activity relationships of (1 -> 6)-beta-d-glucan, and indicate (1 -> 6)-beta-d-glucans from b. inquinans (fries) are potential immunostimulating agents. (c) 2012 elsevier ltd. all rights reserved. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, applied ; chemistry, organic ; polymer science |
| 研究领域[WOS] | chemistry ; polymer science |
| 关键词[WOS] | beta-glucan receptor ; edible mushroom ; polysaccharides ; recognition ; dectin-1 ; extract ; bodies |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000317148200026 |
| 公开日期 | 2014-05-09 |
| 源URL | [http://ir.nwipb.ac.cn/handle/363003/3950]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 作者单位 | 1.NE Normal Univ, Sch Life Sci, Changchun 130022, Peoples R China 2.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining 810008, Peoples R China |
| 推荐引用方式 GB/T 7714 | Bi, Hongtao,Gao, Tingting,Liu, Dongbo,et al. Structures of (1 -> 6)-beta-D-glucans from Bulgaria inquinans (Fries) and their immunological activities[J]. carbohydrate polymers,2013,93(2):547-552. |
| APA | Bi, Hongtao,Gao, Tingting,Liu, Dongbo,Tai, Guihua,Wei, Min,&Zhou, Yifa.(2013).Structures of (1 -> 6)-beta-D-glucans from Bulgaria inquinans (Fries) and their immunological activities.carbohydrate polymers,93(2),547-552. |
| MLA | Bi, Hongtao,et al."Structures of (1 -> 6)-beta-D-glucans from Bulgaria inquinans (Fries) and their immunological activities".carbohydrate polymers 93.2(2013):547-552. |
入库方式： OAI收割
来源：西北高原生物研究所
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