Diterpenoids from Isodon sculponeatus
文献类型：期刊论文
| 作者 | Jiang, Hua-Yi1,2; Wang, Wei-Guang1; Zhou, Min1,2; Wu, Hai-Yan1,2; Zhan, Rui1; Li, Xiao-Nian1; Du, Xue1; Li, Yan1 ; Pu, Jian-Xin1; Sun, Han-Dong1
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| 刊名 | FITOTERAPIA
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| 出版日期 | 2014-03-01 |
| 卷号 | 93期号:93页码:142-149 |
| 关键词 | Isodon sculponeatus Diterpenoids X-ray diffraction Cytotoxicity Anti-inflammatory activity |
| 英文摘要 | Phytochemical investigation of the aerial parts of Isodon sculponeatus afforded six new 7,20-epoxy-ent-kauranoids, sculponins U-Z (1-6), and 11 known diterpenoids (7-17). The structures of these new compounds were elucidated primarily by means of extensive spectroscopic analysis, and the absolute configuration of 1 was determined by single crystal X-ray diffraction. Compound 5 exhibited weak cytotoxic activity against HL-60, SMMC-7721, MCF-7, and SW-480 cell lines, and it also inhibited NO production in LPS-stimulated RAW264.7 cells, with IC50, value of 13.8 mu M. (C) 2014 Elsevier B.V. All rights reserved. |
| 类目[WOS] | Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Pharmacology & Pharmacy |
| 关键词[WOS] | ENT-KAURANE DITERPENOIDS ; 6,7-SECO-ENT-KAURANOIDS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000333494500018 |
| 公开日期 | 2014-05-16 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/18056]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jiang, Hua-Yi,Wang, Wei-Guang,Zhou, Min,et al. Diterpenoids from Isodon sculponeatus[J]. FITOTERAPIA,2014,93(93):142-149. |
| APA | Jiang, Hua-Yi.,Wang, Wei-Guang.,Zhou, Min.,Wu, Hai-Yan.,Zhan, Rui.,...&Sun, Han-Dong.(2014).Diterpenoids from Isodon sculponeatus.FITOTERAPIA,93(93),142-149. |
| MLA | Jiang, Hua-Yi,et al."Diterpenoids from Isodon sculponeatus".FITOTERAPIA 93.93(2014):142-149. |
入库方式： OAI收割
来源：昆明植物研究所
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