Estrogen-like response of perfluorooctyl iodide in male medaka (Oryzias latipes) based on hepatic vitellogenin induction
文献类型：期刊论文
| 作者 | Wang, Yichen ; Zhou, Qunfang ; Wang, Chang ; Yin, Nuoya ; Li, Zhuona ; Liu, Jiyan ; Jiang, Guibin |
| 刊名 | ENVIRONMENTAL TOXICOLOGY
 |
| 出版日期 | 2013 |
| 卷号 | 28期号:10页码:571-578 |
| 通讯作者 | Jiang, GB |
| 中文摘要 | Using the in vivo male medaka model, we investigated the estrogen-like response of perfluorooctyl iodide (PFOI) which is a potential source of perfluorinated carboxylic acids. Using real-time quantitative polymerase chain reaction, the expression levels of related estrogenic genes including estrogenic receptor (ER), ER, vitellogenin I (VTG I), and VTG II in the livers of male medaka exposed to PFOI were analyzed. The results showed that PFOI upregulated the expression levels of the tested genes in a dose-dependent manner. VTG protein levels increased in both dose- and time-dependent manners due to PFOI exposure. The results suggested that PFOI is a potential estrogenic compound. (c) 2011 Wiley Periodicals, Inc. Environ Toxicol 28: 571-578, 2013. |
| 收录类别 | SCI |
| WOS记录号 | WOS:000324114900004 |
| 公开日期 | 2014-06-06 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/7470]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Wang, Yichen,Zhou, Qunfang,Wang, Chang,et al. Estrogen-like response of perfluorooctyl iodide in male medaka (Oryzias latipes) based on hepatic vitellogenin induction[J]. ENVIRONMENTAL TOXICOLOGY,2013,28(10):571-578. |
| APA | Wang, Yichen.,Zhou, Qunfang.,Wang, Chang.,Yin, Nuoya.,Li, Zhuona.,...&Jiang, Guibin.(2013).Estrogen-like response of perfluorooctyl iodide in male medaka (Oryzias latipes) based on hepatic vitellogenin induction.ENVIRONMENTAL TOXICOLOGY,28(10),571-578. |
| MLA | Wang, Yichen,et al."Estrogen-like response of perfluorooctyl iodide in male medaka (Oryzias latipes) based on hepatic vitellogenin induction".ENVIRONMENTAL TOXICOLOGY 28.10(2013):571-578. |
入库方式： OAI收割
来源：生态环境研究中心
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