Damage of DNA ends induced by mechanical force during AFM nano-manipulation
文献类型：期刊论文
| 作者 | Duan Na（段娜） ; Wang Xinyan ; Zhang Chen ; Zhang Yi（张益） ; Hu Jun（胡钧） |
| 刊名 | NUCLEAR SCIENCE AND TECHNIQUES
 |
| 出版日期 | 2013 |
| 卷号 | 24期号:1 |
| ISSN号 | 1001-8042; 2210-3147 |
| 英文摘要 | An experimental and statistical study was carried out to explore the effects of mechanical forces on the ends of linear double-stranded DNA (dsDNA) fragments. Mechanical force was applied onto individual DNA molecules during atomic force microscope (AFM)-based picking-up manipulation. By comparing the PCR efficiency of two DNA fragments with primers either at ends or at the inner regions, it was found that the ends of DNA fragments were damaged during picking-up process. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000328921400006 |
| 公开日期 | 2014-06-13 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/13700]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | Duan Na,Wang Xinyan,Zhang Chen,et al. Damage of DNA ends induced by mechanical force during AFM nano-manipulation[J]. NUCLEAR SCIENCE AND TECHNIQUES,2013,24(1). |
| APA | Duan Na,Wang Xinyan,Zhang Chen,Zhang Yi,&Hu Jun.(2013).Damage of DNA ends induced by mechanical force during AFM nano-manipulation.NUCLEAR SCIENCE AND TECHNIQUES,24(1). |
| MLA | Duan Na,et al."Damage of DNA ends induced by mechanical force during AFM nano-manipulation".NUCLEAR SCIENCE AND TECHNIQUES 24.1(2013). |
入库方式： OAI收割
来源：上海应用物理研究所
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