Preparation and osteogenic properties of magnesium calcium phosphate biocement scaffolds for bone regeneration
文献类型:期刊论文
作者 | Li, X. ; Niu, Y. ; Guo, H. ; Chen, H. ; Li, F. ; Zhang, J. ; Chen, W. ; Wu, Z. ; Deng, Y. ; Wei, J. ; Liu, C. |
刊名 | JOURNAL OF INSTRUMENTATION |
出版日期 | 2013 |
卷号 | 8 |
ISSN号 | 1748-0221 |
英文摘要 | The regenerative treatment of large osseous defects remains a formidable challenge in today. In the present study, we have synthesized biodegradable magnesium calcium phosphate biocement (MCPB) scaffolds with interconnected macroporous structure (100-600 mu m), as well as good bioactivity, biocompatibility and proper degradatibility. The results revealed that the porosity increased from 52% to 80% of MCPB scaffolds while the compressive strength decreased from 6.1MPa to 1.2MPa. We further assessed the effects of scaffolds on the rabbit femur cavity defect model in vivo by using synchrotron radiation X-ray microCT and microCT imaging, indicating that the MCPB scaffolds underwent gradually degradation and promoted the extensive neo-bone formation. |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000322572900010 |
公开日期 | 2014-06-13 |
源URL | [http://ir.sinap.ac.cn/handle/331007/13861] |
专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
推荐引用方式 GB/T 7714 | Li, X.,Niu, Y.,Guo, H.,et al. Preparation and osteogenic properties of magnesium calcium phosphate biocement scaffolds for bone regeneration[J]. JOURNAL OF INSTRUMENTATION,2013,8. |
APA | Li, X..,Niu, Y..,Guo, H..,Chen, H..,Li, F..,...&Liu, C..(2013).Preparation and osteogenic properties of magnesium calcium phosphate biocement scaffolds for bone regeneration.JOURNAL OF INSTRUMENTATION,8. |
MLA | Li, X.,et al."Preparation and osteogenic properties of magnesium calcium phosphate biocement scaffolds for bone regeneration".JOURNAL OF INSTRUMENTATION 8(2013). |
入库方式: OAI收割
来源:上海应用物理研究所
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