Terahertz identification and quantification of penicillamine enantiomers
文献类型：期刊论文
| 作者 | Ji Te ; Zhao Hongwei ; Han Pengyu ; Chen Min ; Xiao Tiqiao |
| 刊名 | NUCLEAR SCIENCE AND TECHNIQUES
 |
| 出版日期 | 2013 |
| 卷号 | 24期号:1 |
| ISSN号 | 1001-8042; 2210-3147 |
| 英文摘要 | Identification and characterization of L-, D- and DL- penicillamine were demonstrated by Terahertz time-domain spectroscopy (THz-TDS). To understand the physical origins of the low frequency resonant modes, the density functional theory (DFT) was adopted for theoretical calculation. It was found that the collective THz frequency motions were decided by the intramolecular and intermolecular hydrogen bond interactions. Moreover, the quantification of penicillamine enantiomers mixture was demonstrated by a THz spectra fitting method with a relative error of less than 3.5%. This technique can be a valuable tool for the discrimination and quantification of chiral drugs in pharmaceutical industry. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000328921400003 |
| 公开日期 | 2014-06-13 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/13949]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | Ji Te,Zhao Hongwei,Han Pengyu,et al. Terahertz identification and quantification of penicillamine enantiomers[J]. NUCLEAR SCIENCE AND TECHNIQUES,2013,24(1). |
| APA | Ji Te,Zhao Hongwei,Han Pengyu,Chen Min,&Xiao Tiqiao.(2013).Terahertz identification and quantification of penicillamine enantiomers.NUCLEAR SCIENCE AND TECHNIQUES,24(1). |
| MLA | Ji Te,et al."Terahertz identification and quantification of penicillamine enantiomers".NUCLEAR SCIENCE AND TECHNIQUES 24.1(2013). |
入库方式： OAI收割
来源：上海应用物理研究所
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