Ultra-sensitive nucleic acids detection with electrical nanosensors based on CMOS-compatible silicon nanowire field-effect transistors
文献类型：期刊论文
| 作者 | Lu, Na ; Gao, Anran ; Dai, Pengfei ; Li, Tie ; Wang, Yi ; Gao, Xiuli ; Song, Shiping ; Fan, Chunhai ; Wang, Yuelin |
| 刊名 | METHODS
 |
| 出版日期 | 2013 |
| 卷号 | 63期号:3页码:CONCATENATE(Sheet1!I384,-Sheet1!J384) |
| ISSN号 | 1046-2023; 1095-9130 |
| 英文摘要 | Silicon nanowire field-effect transistors (SiNW-FETs) have recently emerged as a type of powerful nanoelectronic biosensors due to their ultrahigh sensitivity, selectivity, label-free and real-time detection capabilities. Here, we present a protocol as well as guidelines for detecting DNA with complementary metal oxide semiconductor (CMOS) compatible SiNW-FET sensors. SiNWs with high surface-to-volume ratio and controllable sizes were fabricated with an anisotropic self-stop etching technique. Probe DNA molecules specific for the target DNA were covalently modified onto the surface of the SiNWs. The SiNW-FET nanosensors exhibited an ultrahigh sensitivity for detecting the target DNA as low as 1 fM and good selectivity for discrimination from one-base mismatched DNA. (C) 2013 Elsevier Inc. All rights reserved. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000326135800003 |
| 公开日期 | 2014-06-13 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/13978]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | Lu, Na,Gao, Anran,Dai, Pengfei,et al. Ultra-sensitive nucleic acids detection with electrical nanosensors based on CMOS-compatible silicon nanowire field-effect transistors[J]. METHODS,2013,63(3):CONCATENATE(Sheet1!I384,-Sheet1!J384). |
| APA | Lu, Na.,Gao, Anran.,Dai, Pengfei.,Li, Tie.,Wang, Yi.,...&Wang, Yuelin.(2013).Ultra-sensitive nucleic acids detection with electrical nanosensors based on CMOS-compatible silicon nanowire field-effect transistors.METHODS,63(3),CONCATENATE(Sheet1!I384,-Sheet1!J384). |
| MLA | Lu, Na,et al."Ultra-sensitive nucleic acids detection with electrical nanosensors based on CMOS-compatible silicon nanowire field-effect transistors".METHODS 63.3(2013):CONCATENATE(Sheet1!I384,-Sheet1!J384). |
入库方式： OAI收割
来源：上海应用物理研究所
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