Hepatoprotective Effects of Triterpenoids from Ganoderma cochlear
文献类型：期刊论文
| 作者 | Peng, Xing-Rong1,2; Liu, Jie-Qing1; Wang, Cui-Fang1; Li, Xu-Yang1,2; Shu, Yi1; Zhou, Lin1; Qiu, Ming-Hua1
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| 刊名 | JOURNAL OF NATURAL PRODUCTS
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| 出版日期 | 2014-04-01 |
| 卷号 | 77期号:4页码:737-743 |
| ISSN号 | 0163-3864 |
| 关键词 | ANTITUMOR-PROMOTING ACTIVITY INONOTUS-OBLIQUUS SCLEROTIA MUSHROOM SINENSE |
| 通讯作者 | Qiu,MH (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China. ; mhchiu@mail.kib.ac.cn |
| 英文摘要 | Two novel trinorlanostanes, cochlates A and B (1 and 2), with a 3,4-seco-9,10-seco-9,19-cyclo skeleton, as well as six new triterpenoids, fornicatins D-F (3-5) and ganodercochlearins A-C (6-8), together with five known triterpenoids (9-13), were obtained from the fruiting bodies of Ganoderma cochlear. The structural elucidation was achieved by interpretation of spectroscopic data, and compounds 2 and 7a were further characterized by X-ray crystallographic analysis. Fornicatins A, D, and F (10, 3, and 5) and fredelin (13) lowered the ALT and AST levels in HepG2 cells treated with H2O2, suggesting that they could display in vivo hepatoprotective activities. |
| 学科主题 | Plant Sciences ; Pharmacology & Pharmacy |
| 类目[WOS] | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Plant Sciences ; Pharmacology & Pharmacy |
| 关键词[WOS] | ANTITUMOR-PROMOTING ACTIVITY ; INONOTUS-OBLIQUUS ; SCLEROTIA ; MUSHROOM ; SINENSE |
| 资助信息 | General Program of NSFC [81172940]; Knowledge Innovation Program of the CAS [KSCX2-YW-G-038, KSCX2-YW-R-194]; Top Talents Program from the Department of Science and Technology in Yunnan Province [20080A007]; Foundation of State Key Laboratory of Phytochemistry and Plant Resources in West China [P2010-ZZ14] |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000335127200001 |
| 公开日期 | 2014-06-23 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/18120]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Peng, Xing-Rong,Liu, Jie-Qing,Wang, Cui-Fang,et al. Hepatoprotective Effects of Triterpenoids from Ganoderma cochlear[J]. JOURNAL OF NATURAL PRODUCTS,2014,77(4):737-743. |
| APA | Peng, Xing-Rong.,Liu, Jie-Qing.,Wang, Cui-Fang.,Li, Xu-Yang.,Shu, Yi.,...&Qiu, Ming-Hua.(2014).Hepatoprotective Effects of Triterpenoids from Ganoderma cochlear.JOURNAL OF NATURAL PRODUCTS,77(4),737-743. |
| MLA | Peng, Xing-Rong,et al."Hepatoprotective Effects of Triterpenoids from Ganoderma cochlear".JOURNAL OF NATURAL PRODUCTS 77.4(2014):737-743. |
入库方式： OAI收割
来源：昆明植物研究所
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