Biologically Active Dichapetalins from Dichapetalum gelonioides
文献类型：期刊论文
| 作者 | Jing, Shu-Xi1,3; Luo, Shi-Hong1; Li, Chun-Huan1; Hua, Juan1; Wang, Yan-Li2; Niu, Xue-Mei2; Li, Xiao-Nian1; Liu, Yan1; Huang, Chun-Shuai1; Wang, Ying1 |
| 刊名 | JOURNAL OF NATURAL PRODUCTS
 |
| 出版日期 | 2014-04-01 |
| 卷号 | 77期号:4页码:882-893 |
| 关键词 | DEFENSIVE SESTERTERPENOIDS GLANDULAR TRICHOMES TRITERPENOIDS CONSTITUENTS DERIVATIVES HARBOR |
| ISSN号 | 0163-3864 |
| 通讯作者 | Li,SH (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China. ; shli@mail.kib.ac.cn |
| 英文摘要 | A phytochemical investigation of the toxic tropical plant Dichapetalum gelonioides led to the isolation and identification of 14 new dichapetalins (1-14) and the known dichapetalins A (15) and K (16). The structures of the new compounds were determined by analyses of their NMR, MS, electronic circular dichroism, and X-ray diffraction data. The esterification at C-25 by 4-hydroxyphenylpropanoic acid and the hydroxylation at C-2' are unique in this unusual class of natural products. In addition to the known cytotoxicity, an array of biological activities, including antifeedant, nematicidal, antifungal, and NO and AChE inhibitory activities, were observed for this class of compounds. These findings suggested that dichapetalin hybrid triterpenoids as a class have broad biologically active cellular functions including defense against insect herbivores and pathogens. |
| 学科主题 | Plant Sciences ; Pharmacology & Pharmacy |
| 类目[WOS] | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Plant Sciences ; Pharmacology & Pharmacy |
| 关键词[WOS] | DEFENSIVE SESTERTERPENOIDS ; GLANDULAR TRICHOMES ; TRITERPENOIDS ; CONSTITUENTS ; DERIVATIVES ; HARBOR |
| 收录类别 | SCI ; IC |
| 资助信息 | National Basic Research Program of China (973 Program) on Biological Control of Key Crop Pathogenic Nematodes [2013CB127505]; "Hundred Talents Program" of the Chinese Academy of Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000335127200021 |
| 公开日期 | 2014-06-23 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/18121]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Yunnan Univ, Key Lab Conservat & Utilizat Bioresources, Kunming 650091, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jing, Shu-Xi,Luo, Shi-Hong,Li, Chun-Huan,et al. Biologically Active Dichapetalins from Dichapetalum gelonioides[J]. JOURNAL OF NATURAL PRODUCTS,2014,77(4):882-893. |
| APA | Jing, Shu-Xi.,Luo, Shi-Hong.,Li, Chun-Huan.,Hua, Juan.,Wang, Yan-Li.,...&Li, Sheng-Hong.(2014).Biologically Active Dichapetalins from Dichapetalum gelonioides.JOURNAL OF NATURAL PRODUCTS,77(4),882-893. |
| MLA | Jing, Shu-Xi,et al."Biologically Active Dichapetalins from Dichapetalum gelonioides".JOURNAL OF NATURAL PRODUCTS 77.4(2014):882-893. |
入库方式： OAI收割
来源：昆明植物研究所
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