Aniquinazolines A-D, Four New Quinazolinone Alkaloids from Marine-Derived Endophytic Fungus Aspergillus nidulans
文献类型：期刊论文
| 作者 | An, Chun-Yan1,2; Li, Xiao-Ming1; Li, Chun-Shun1; Wang, Ming-Hui1,2; Xu, Gang-Ming1; Wang, Bin-Gui1 ; Wang, BG
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| 刊名 | MARINE DRUGS
 |
| 出版日期 | 2013-07-01 |
| 卷号 | 11期号:7页码:2682-2694 |
| 关键词 | mangrove endophytic fungus Aspergillus nidulans secondary metabolites bioactivity |
| ISSN号 | 1660-3397 |
| 通讯作者 | Wang, BG |
| 中文摘要 | Four new quinazolinone alkaloids, namely, aniquinazolines A-D (1-4), were isolated and identified from the culture of Aspergillus nidulans MA-143, an endophytic fungus obtained from the leaves of marine mangrove plant Rhizophora stylosa. The structures of the new compounds were elucidated by spectroscopic analysis, and their absolute configurations were determined on the basis of chiral HPLC analysis of the acidic hydrolysates. The structure for 1 was confirmed by single-crystal X-ray diffraction analysis. All these compounds were examined for antibacterial and cytotoxic activity as well as brine shrimp (Artemia salina) lethality. |
| 英文摘要 | Four new quinazolinone alkaloids, namely, aniquinazolines A-D (1-4), were isolated and identified from the culture of Aspergillus nidulans MA-143, an endophytic fungus obtained from the leaves of marine mangrove plant Rhizophora stylosa. The structures of the new compounds were elucidated by spectroscopic analysis, and their absolute configurations were determined on the basis of chiral HPLC analysis of the acidic hydrolysates. The structure for 1 was confirmed by single-crystal X-ray diffraction analysis. All these compounds were examined for antibacterial and cytotoxic activity as well as brine shrimp (Artemia salina) lethality. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 学科主题 | Pharmacology & Pharmacy |
| 类目[WOS] | Chemistry, Medicinal |
| 研究领域[WOS] | Pharmacology & Pharmacy |
| 关键词[WOS] | METABOLITES ; ANTIFUNGAL ; FUMIGATUS |
| 收录类别 | SCI |
| 原文出处 | 10.3390/md11072682 |
| 语种 | 英语 |
| WOS记录号 | WOS:000328621500026 |
| 公开日期 | 2014-07-17 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/16528]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Wang, BG |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | An, Chun-Yan,Li, Xiao-Ming,Li, Chun-Shun,et al. Aniquinazolines A-D, Four New Quinazolinone Alkaloids from Marine-Derived Endophytic Fungus Aspergillus nidulans[J]. MARINE DRUGS,2013,11(7):2682-2694. |
| APA | An, Chun-Yan.,Li, Xiao-Ming.,Li, Chun-Shun.,Wang, Ming-Hui.,Xu, Gang-Ming.,...&Wang, BG.(2013).Aniquinazolines A-D, Four New Quinazolinone Alkaloids from Marine-Derived Endophytic Fungus Aspergillus nidulans.MARINE DRUGS,11(7),2682-2694. |
| MLA | An, Chun-Yan,et al."Aniquinazolines A-D, Four New Quinazolinone Alkaloids from Marine-Derived Endophytic Fungus Aspergillus nidulans".MARINE DRUGS 11.7(2013):2682-2694. |
入库方式： OAI收割
来源：海洋研究所
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