Cytotoxic Anthranilic Acid Derivatives from Deep Sea Sediment-Derived Fungus Penicillium paneum SD-44
文献类型：期刊论文
| 作者 | Li, Chun-Shun1; Li, Xiao-Ming1; Gao, Shu-Shan1; Lu, Yan-Hua2; Wang, Bin-Gui1 ; Wang, BG
|
| 刊名 | MARINE DRUGS
 |
| 出版日期 | 2013-08-01 |
| 卷号 | 11期号:8页码:3068-3076 |
| ISSN号 | 1660-3397 |
| 关键词 | marine fungus sediment anthranilic acid Penicillium paneum cytotoxicity |
| 通讯作者 | Wang, BG |
| 中文摘要 | Five new anthranilic acid derivatives, penipacids A-E (1-5), together with one known analogue (6), which was previously synthesized, were characterized from the ethyl acetate extract of the marine sediment-derived fungus Penicillium paneum SD-44. Their structures were elucidated mainly by extensive NMR spectroscopic and mass spectrometric analysis. The cytotoxicity and antimicrobial activity of the isolated compounds were evaluated. Compounds 1, and 5 exhibited inhibitory activity against human colon cancer RKO cell line, while compound 6 displayed cytotoxic activity against Hela cell line. |
| 英文摘要 | Five new anthranilic acid derivatives, penipacids A-E (1-5), together with one known analogue (6), which was previously synthesized, were characterized from the ethyl acetate extract of the marine sediment-derived fungus Penicillium paneum SD-44. Their structures were elucidated mainly by extensive NMR spectroscopic and mass spectrometric analysis. The cytotoxicity and antimicrobial activity of the isolated compounds were evaluated. Compounds 1, and 5 exhibited inhibitory activity against human colon cancer RKO cell line, while compound 6 displayed cytotoxic activity against Hela cell line. |
| 学科主题 | Pharmacology & Pharmacy |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Chemistry, Medicinal |
| 研究领域[WOS] | Pharmacology & Pharmacy |
| 关键词[WOS] | NATURAL-PRODUCTS ; ANTIBACTERIAL ; METABOLITE ; INHIBITORS ; COMPLEXES ; ALKALOIDS |
| 收录类别 | SCI |
| 原文出处 | 10.3390/md11083068 |
| 语种 | 英语 |
| WOS记录号 | WOS:000330521300024 |
| 公开日期 | 2014-07-17 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/16556]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Wang, BG |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Chun-Shun,Li, Xiao-Ming,Gao, Shu-Shan,et al. Cytotoxic Anthranilic Acid Derivatives from Deep Sea Sediment-Derived Fungus Penicillium paneum SD-44[J]. MARINE DRUGS,2013,11(8):3068-3076. |
| APA | Li, Chun-Shun,Li, Xiao-Ming,Gao, Shu-Shan,Lu, Yan-Hua,Wang, Bin-Gui,&Wang, BG.(2013).Cytotoxic Anthranilic Acid Derivatives from Deep Sea Sediment-Derived Fungus Penicillium paneum SD-44.MARINE DRUGS,11(8),3068-3076. |
| MLA | Li, Chun-Shun,et al."Cytotoxic Anthranilic Acid Derivatives from Deep Sea Sediment-Derived Fungus Penicillium paneum SD-44".MARINE DRUGS 11.8(2013):3068-3076. |
入库方式： OAI收割
来源：海洋研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。