Targeting cellular apoptotic pathway with peptides from marine organisms
文献类型：期刊论文
| 作者 | Zheng, Lanhong1; Lin, Xiukun2; Wu, Ning3; Liu, Ming3; Zheng, Yuan1; Sheng, Jun1; Ji, Xiaofeng1; Sun, Mi1 |
| 刊名 | BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
 |
| 出版日期 | 2013-08-01 |
| 卷号 | 1836期号:1页码:42-48 |
| 关键词 | Apoptosis Marine organisms Peptides |
| ISSN号 | 0304-419X |
| 通讯作者 | Lin, XK |
| 中文摘要 | Apoptosis is a critical defense mechanism against the formation and progression of cancer and exhibits distinct morphological and biochemical traits. Targeting apoptotic pathways becomes an intriguing strategy for the development of chemotherapeutic agents. Peptides from marine organisms have become important sources in the discovery of antitumor drugs, especially when modern technology makes it more and more feasible to collect organisms from seas. This primer summarizes several marine peptides, based on their effects on apoptotic signaling pathways, although most of these peptides have not yet been studied in depth for their mechanisms of action. Novel peptides that induce an apoptosis signal pathway are presented in association with their pharmacological properties. (C) 2013 Elsevier B.V. All rights reserved. |
| 英文摘要 | Apoptosis is a critical defense mechanism against the formation and progression of cancer and exhibits distinct morphological and biochemical traits. Targeting apoptotic pathways becomes an intriguing strategy for the development of chemotherapeutic agents. Peptides from marine organisms have become important sources in the discovery of antitumor drugs, especially when modern technology makes it more and more feasible to collect organisms from seas. This primer summarizes several marine peptides, based on their effects on apoptotic signaling pathways, although most of these peptides have not yet been studied in depth for their mechanisms of action. Novel peptides that induce an apoptosis signal pathway are presented in association with their pharmacological properties. (C) 2013 Elsevier B.V. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 学科主题 | Biochemistry & Molecular Biology ; Biophysics ; Oncology |
| 类目[WOS] | Biochemistry & Molecular Biology ; Biophysics ; Oncology |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Biophysics ; Oncology |
| 关键词[WOS] | BCL-2 FAMILY PROTEINS ; FACTOR-KAPPA-B ; CANCER-THERAPY ; BRENTUXIMAB VEDOTIN ; DIDEMNIN-B ; IN-VITRO ; PM02734 ELISIDEPSIN ; SOMOCYSTINAMIDE-A ; ANTICANCER AGENTS ; CLINICAL-TRIALS |
| 收录类别 | SCI |
| 原文出处 | 10.1016/j.bbcan.2013.02.006 |
| 语种 | 英语 |
| WOS记录号 | WOS:000320475800004 |
| 公开日期 | 2014-07-17 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/16639]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 作者单位 | 1.Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, Qingdao 266071, Peoples R China 2.Capital Med Univ, Dept Pharmacol, Beijing 100069, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, Qingdao, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zheng, Lanhong,Lin, Xiukun,Wu, Ning,et al. Targeting cellular apoptotic pathway with peptides from marine organisms[J]. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER,2013,1836(1):42-48. |
| APA | Zheng, Lanhong.,Lin, Xiukun.,Wu, Ning.,Liu, Ming.,Zheng, Yuan.,...&Sun, Mi.(2013).Targeting cellular apoptotic pathway with peptides from marine organisms.BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER,1836(1),42-48. |
| MLA | Zheng, Lanhong,et al."Targeting cellular apoptotic pathway with peptides from marine organisms".BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER 1836.1(2013):42-48. |
入库方式： OAI收割
来源：海洋研究所
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