Synthesis and antifungal evaluation of (1,2,3-triazol-4-yl)methyl nicotinate chitosan
文献类型：期刊论文
| 作者 | Qin, Yukun1 ; Liu, Song1; Xing, Ronge1; Li, Kecheng1,2; Yu, Huahua1; Li, Pengcheng1
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| 刊名 | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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| 出版日期 | 2013-10-01 |
| 卷号 | 61页码:58-62 |
| 关键词 | Chitosan 1 Click reaction Characterization Antifungal activity 2 3-Triazole |
| ISSN号 | 0141-8130 |
| 通讯作者 | Xing, RG |
| 中文摘要 | With an aim to discover novel chitosan derivatives with significant activities against crop-threatening fungi, (1,2,3-triazol-4-yl)methyl nicotinate chitosan (TAMNCS) was prepared via azide-alkyne click reaction. Its structure was characterized by FT-IR, H-1 NMR, elemental analysis, DSC, and SEM. In vitro antifungal properties of TAMNCS against Rhizoctonia solani Kuhn (R. solani), Stemphylium solani weber (S. solani), and Alternaria porri (A. porri) were studied at the concentrations ranged from 0.25 mg/mL to 1.0 mg/mL. Experiments conducted displayed the derivative had obviously enhanced antifungal activity after chemical modification compared with original chitosan. Moreover, it was shown that TAMNCS can 94.2% inhibit growth of A. pouf at 1.0 mg/mL, while dose at which the fungicide triadimefon had lower inhibitory index (62.2%). The primary antifungal results described here indicate this derivative may be a promising candidate as an antifungal agent. (C). 2013 Elsevier B.V. All rights reserved. |
| 英文摘要 | With an aim to discover novel chitosan derivatives with significant activities against crop-threatening fungi, (1,2,3-triazol-4-yl)methyl nicotinate chitosan (TAMNCS) was prepared via azide-alkyne click reaction. Its structure was characterized by FT-IR, H-1 NMR, elemental analysis, DSC, and SEM. In vitro antifungal properties of TAMNCS against Rhizoctonia solani Kuhn (R. solani), Stemphylium solani weber (S. solani), and Alternaria porri (A. porri) were studied at the concentrations ranged from 0.25 mg/mL to 1.0 mg/mL. Experiments conducted displayed the derivative had obviously enhanced antifungal activity after chemical modification compared with original chitosan. Moreover, it was shown that TAMNCS can 94.2% inhibit growth of A. pouf at 1.0 mg/mL, while dose at which the fungicide triadimefon had lower inhibitory index (62.2%). The primary antifungal results described here indicate this derivative may be a promising candidate as an antifungal agent. (C). 2013 Elsevier B.V. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 学科主题 | Biochemistry & Molecular Biology |
| 类目[WOS] | Biochemistry & Molecular Biology |
| 研究领域[WOS] | Biochemistry & Molecular Biology |
| 关键词[WOS] | CLICK CHEMISTRY ; CARBOXYMETHYL CHITOSAN ; THIOUREA DERIVATIVES ; CHITIN |
| 收录类别 | SCI |
| 原文出处 | 10.1016/j.ijbiomac.2013.05.023 |
| 语种 | 英语 |
| WOS记录号 | WOS:000326660700009 |
| 公开日期 | 2014-07-17 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/16724]  |
| 专题 | 海洋研究所_海洋生物技术研发中心 海洋研究所_海洋环境工程技术研究发展中心 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qin, Yukun,Liu, Song,Xing, Ronge,et al. Synthesis and antifungal evaluation of (1,2,3-triazol-4-yl)methyl nicotinate chitosan[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2013,61:58-62. |
| APA | Qin, Yukun,Liu, Song,Xing, Ronge,Li, Kecheng,Yu, Huahua,&Li, Pengcheng.(2013).Synthesis and antifungal evaluation of (1,2,3-triazol-4-yl)methyl nicotinate chitosan.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,61,58-62. |
| MLA | Qin, Yukun,et al."Synthesis and antifungal evaluation of (1,2,3-triazol-4-yl)methyl nicotinate chitosan".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 61(2013):58-62. |
入库方式： OAI收割
来源：海洋研究所
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