Spectrum of Fates: a new approach to the study of the developing zebrafish retina
文献类型：期刊论文
| 作者 | Almeida, AD ; Boije, H ; Chow, RW ; He, J ; Tham, J ; Suzuki, SC ; Harris, WA |
| 刊名 | DEVELOPMENT
 |
| 出版日期 | 2014 |
| 卷号 | 141期号:9页码:1971-1980 |
| 关键词 | CELLS IN-VIVO XENOPUS RETINA NEURONAL PROGENITORS GANGLION-CELLS HOMEOBOX GENE MULLER GLIA RAT RETINA RECONSTRUCTION LINEAGES HOMOLOG |
| ISSN号 | 0950-1991 |
| 通讯作者 | Harris, WA (reprint author), Univ Cambridge, Dept Physiol Dev & Neurosci, Cambridge CB2 3DY, England.,wah20@cam.ac.uk |
| 英文摘要 | The ability to image cells live and in situ as they proliferate and differentiate has proved to be an invaluable asset to biologists investigating developmental processes. Here, we describe a Spectrum of Fates approach that allows the identification of all the major neuronal subtypes in the zebrafish retina simultaneously. Spectrum of Fates is based on the combinatorial expression of differently coloured fluorescent proteins driven by the promoters of transcription factors that are expressed in overlapping subsets of retinal neurons. Here, we show how a Spectrum of Fates approach can be used to assess various aspects of neural development, such as developmental waves of differentiation, neuropil development, lineage tracing and hierarchies of fates in the developing zebrafish retina. |
| 学科主题 | Developmental Biology |
| 收录类别 | SCI |
| 资助信息 | Wellcome Trust |
| 语种 | 英语 |
| 公开日期 | 2014-07-30 |
| 源URL | [http://ir.sibs.ac.cn/handle/331001/2609]  |
| 专题 | 上海神经科学研究所_神经所(总) |
| 推荐引用方式 GB/T 7714 | Almeida, AD,Boije, H,Chow, RW,et al. Spectrum of Fates: a new approach to the study of the developing zebrafish retina[J]. DEVELOPMENT,2014,141(9):1971-1980. |
| APA | Almeida, AD.,Boije, H.,Chow, RW.,He, J.,Tham, J.,...&Harris, WA.(2014).Spectrum of Fates: a new approach to the study of the developing zebrafish retina.DEVELOPMENT,141(9),1971-1980. |
| MLA | Almeida, AD,et al."Spectrum of Fates: a new approach to the study of the developing zebrafish retina".DEVELOPMENT 141.9(2014):1971-1980. |
入库方式： OAI收割
来源：上海神经科学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。