Merging of covalent cross-linking and biomimetic mineralization into an LBL self-assembly process for the construction of robust organic-inorganic hybrid microcapsules
文献类型：期刊论文
| 作者 | Tian, Chunyong1,2; Zhang, Chunhong1; Wu, Hong1,4; Song, Yixuan1; Shi, Jiafu3; Wang, Xiaoli1; Song, Xiaokai1; Yang, Chen1; Jiang, Zhongyi1,2,4 |
| 刊名 | JOURNAL OF MATERIALS CHEMISTRY B
 |
| 出版日期 | 2014 |
| 卷号 | 2期号:27页码:4346-4355 |
| 关键词 | MULTI LAYERS SILICA POLYMER ENCAPSULATION SURFACES IMMOBILIZATION CAPSULES COATINGS DELIVERY DIATOMS |
| ISSN号 | 2050-750X |
| 其他题名 | J. Mat. Chem. B |
| 中文摘要 | A mild and efficient method for the construction of robust organic-inorganic hybrid microcapsules was developed by merging of covalent cross-linking and biomimetic mineralization into a layer-by-layer (LBL) self-assembly process. The diatom cell-inspired microcapsule structure had a biocompatible inner organic layer which could create a suitable microenvironment for biologically active substances inside the microcapsules and an inorganic layer which could function as a supporting membrane to maintain the intact morphology of the microcapsules. When in 40% PSS solution, only 5% of the hybrid microcapsules were deformed indicating that the hybrid microcapsule had a higher mechanical stability. The combination of the advantages of both the organic layer and the inorganic layer was applied for the immobilization of catalase (CAT). After being reused 7 times, the CAT in the hybrid microcapsules retained 78% of its initial activity. A buffering effect was created by the capsule wall and the immobilized CAT had a higher pH stability than the free CAT. After storing for 45 days, the CAT in the hybrid microcapsules retained 78% of its initial activity. It is envisaged that the as-prepared hybrid microcapsules can be extended to many applications such as biocatalysis, drug/gene delivery and biosensor fields. |
| 英文摘要 | A mild and efficient method for the construction of robust organic-inorganic hybrid microcapsules was developed by merging of covalent cross-linking and biomimetic mineralization into a layer-by-layer (LBL) self-assembly process. The diatom cell-inspired microcapsule structure had a biocompatible inner organic layer which could create a suitable microenvironment for biologically active substances inside the microcapsules and an inorganic layer which could function as a supporting membrane to maintain the intact morphology of the microcapsules. When in 40% PSS solution, only 5% of the hybrid microcapsules were deformed indicating that the hybrid microcapsule had a higher mechanical stability. The combination of the advantages of both the organic layer and the inorganic layer was applied for the immobilization of catalase (CAT). After being reused 7 times, the CAT in the hybrid microcapsules retained 78% of its initial activity. A buffering effect was created by the capsule wall and the immobilized CAT had a higher pH stability than the free CAT. After storing for 45 days, the CAT in the hybrid microcapsules retained 78% of its initial activity. It is envisaged that the as-prepared hybrid microcapsules can be extended to many applications such as biocatalysis, drug/gene delivery and biosensor fields. |
| WOS标题词 | Science & Technology ; Technology |
| 类目[WOS] | Materials Science, Biomaterials |
| 研究领域[WOS] | Materials Science |
| 关键词[WOS] | MULTI LAYERS ; SILICA ; POLYMER ; ENCAPSULATION ; SURFACES ; IMMOBILIZATION ; CAPSULES ; COATINGS ; DELIVERY ; DIATOMS |
| 收录类别 | SCI |
| 原文出处 | |
| 语种 | 英语 |
| WOS记录号 | WOS:000338124900016 |
| 公开日期 | 2014-08-28 |
| 版本 | 出版稿 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/10967]  |
| 专题 | 过程工程研究所_研究所（批量导入） |
| 作者单位 | 1.Tianjin Univ, Sch Chem Engn & Technol, Minist Educ, Key Lab Green Chem Technol, Tianjin 300072, Peoples R China 2.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China 3.Tianjin Univ, Sch Environm Sci & Engn, Tianjin 300072, Peoples R China 4.Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300072, Peoples R China |
| 推荐引用方式 GB/T 7714 | Tian, Chunyong,Zhang, Chunhong,Wu, Hong,et al. Merging of covalent cross-linking and biomimetic mineralization into an LBL self-assembly process for the construction of robust organic-inorganic hybrid microcapsules[J]. JOURNAL OF MATERIALS CHEMISTRY B,2014,2(27):4346-4355. |
| APA | Tian, Chunyong.,Zhang, Chunhong.,Wu, Hong.,Song, Yixuan.,Shi, Jiafu.,...&Jiang, Zhongyi.(2014).Merging of covalent cross-linking and biomimetic mineralization into an LBL self-assembly process for the construction of robust organic-inorganic hybrid microcapsules.JOURNAL OF MATERIALS CHEMISTRY B,2(27),4346-4355. |
| MLA | Tian, Chunyong,et al."Merging of covalent cross-linking and biomimetic mineralization into an LBL self-assembly process for the construction of robust organic-inorganic hybrid microcapsules".JOURNAL OF MATERIALS CHEMISTRY B 2.27(2014):4346-4355. |
入库方式： OAI收割
来源：过程工程研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。