Preparation of Uniform Microspheres and Microcapsules by Modified Emulsification Process
文献类型：会议论文
| 作者 | Ma, G. H.; Yang, J.; Lv, P. P.; Wang, L. Y.; Wei, W.; Tian, R.; Wu, J.; Su, Z. G. |
| 出版日期 | 2010 |
| 会议名称 | 2nd International Symposium on Advanced Particles/19th Iketani Conference |
| 会议日期 | APR 26-29, 2009 |
| 会议地点 | Keio Univ, Yokohama, JAPAN |
| 关键词 | magnetite microcapsule microsphere modified membrane emulsification technique uniform SIZED CHITOSAN MICROSPHERES SOLVENT EVAPORATION METHOD MEMBRANE EMULSIFICATION PLA MICROCAPSULES PROTEIN DRUG DELIVERY |
| 页码 | 41-48 |
| 其他题名 | Macromol. Symp. |
| 中文摘要 | Uniform microspheres and microcapsules have been prepared by developing a direct membrane emulsification technique from O/W, W/O and W/O/W emulsions in previous studies, and have been applied in bio-separation and drug delivery systems. The diameter can be controlled from several microns to above loo microns. However, smaller microsphere with submicron size, especially from W/O/W emulsion was difficult to be prepared. In this article, a modified emulsification technique was developed to overcome the problem. That is, a pre-emulsion (W/O or W/O/W) with broad size distribution of droplets was prepared firstly by homogenization, sonification or mechanical stirring method, then the pre-emulsion was pressed through the uniform pores of a Shirasu Porous Glass (SPG) membrane to obtain relatively uniform smaller droplets, finally the droplets were solidified to form uniform microsphere or microcapsule. Uniform chitosan microsphere and poly(lactic-glycolic acid) (PLGA) microcapsule with submicron size were prepared from W/O and W/O/W emulsions, respectively. Further more, uniform polymer-magnetite microcapsule was prepared by combining this technique and a new post-precipitation process of magnetite. |
| 收录类别 | ISTP |
| 会议网址 | |
| 会议录 | SymposiaMACROMOLECULAR SYMPOSIA 卷: 288 页: 41-48
 |
| 语种 | 英语 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/11190]  |
| 专题 | 过程工程研究所_研究所（批量导入） |
| 推荐引用方式 GB/T 7714 |
Ma, G. H.,Yang, J.,Lv, P. P.,et al. Preparation of Uniform Microspheres and Microcapsules by Modified Emulsification Process[C]. 见:2nd International Symposium on Advanced Particles/19th Iketani Conference. Keio Univ, Yokohama, JAPAN. APR 26-29, 2009. |
入库方式： OAI收割
来源：过程工程研究所
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