Simulation of protein crystallization on the basis of thermodynamic model
文献类型：会议论文
| 作者 | Zhang, X. P.; Zhang, S. J.; Li, C. S. |
| 出版日期 | 2003 |
| 会议名称 | 8th International Symposium on Process Systems Engineering |
| 会议日期 | JUN 22-27, 2003 |
| 会议地点 | KUNMING, PEOPLES R CHINA |
| 关键词 | simulation protein crystallization thermodynamic solubility lysozyme UNIQUAC equation liquid-solid phase equilibrium EGG-WHITE LYSOZYME PHASE-EQUILIBRIA SOLUBILITY OVALBUMIN |
| 页码 | 1240-1245 |
| 中文摘要 | A solid-liquid phase equilibrium thermodynamic model of lysozyme-salt-water system was proposed. UNIQUAC model is applied to calculate the liquid phase activity coefficients. With micro-genetic algorithm, the binary interaction parameters of UNIQUAC model were estimated. The calculated results were agreed well with the experimental data, the average relative deviation was 2.32%. Simulating a protein crystallizer is one of the main tasks for designing and retrofitting a crystallization process. Based on the design task, the simulation of crystallizer was performed considering the thermodynamic model, equipment types and mass material balances. The yield of lysozyme can be obtained. It is meaningful for simulation of protein crystallization process in the industry-scale. |
| 收录类别 | ISTP |
| 会议网址 | |
| 会议录出版者 | Elsevier Science Bv |
| 语种 | 英语 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/11307]  |
| 专题 | 过程工程研究所_研究所（批量导入） |
| 推荐引用方式 GB/T 7714 |
Zhang, X. P.,Zhang, S. J.,Li, C. S.. Simulation of protein crystallization on the basis of thermodynamic model[C]. 见:8th International Symposium on Process Systems Engineering. KUNMING, PEOPLES R CHINA. JUN 22-27, 2003. |
入库方式： OAI收割
来源：过程工程研究所
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