Retention mechanism and enrichment of glycopeptides on titanium dioxide
文献类型：期刊论文
| 作者 | Sheng, Qianying1; Li, Xiuling2; Yin, Wei3; Yu, Long2; Ke, Yanxiong1; Liang, Xinmiao1,2 |
| 刊名 | analytical methods
 |
| 出版日期 | 2013 |
| 卷号 | 5期号:24页码:7072-7080 |
| 产权排序 | 待补充 |
| 通讯作者 | 李秀玲 ; 梁鑫淼 |
| 合作状况 | 英 |
| 英文摘要 | a uniform method for the facile and selective enrichment of glycopeptides with titanium dioxide (tio2) is presented. retention mechanisms between glycopeptides and tio2 were explored by checking the influence of acetonitrile content, nh3 center dot h2o concentration and formic acid concentration on the retention of glycopeptides. both hydrophilic interaction and ligand-exchange retention mechanisms between glycopeptides and tio2 were found to be involved. based on this, a uniform method was established for selective enrichment of glycopeptides with tio2. the developed method exhibited high selectivity for n-linked glycopeptides with short to long peptide sequences. this efficient and uniform method will be a valuable tool for post-translational modification in proteomics. |
| WOS标题词 | science & technology ; physical sciences ; life sciences & biomedicine ; technology |
| 学科主题 | 物理化学 |
| 类目[WOS] | chemistry, analytical ; food science & technology ; spectroscopy |
| 研究领域[WOS] | chemistry ; food science & technology ; spectroscopy |
| 关键词[WOS] | hydrophilic interaction chromatography ; glycosylation ; matrix ; peptides ; hplc |
| 收录类别 | SCI |
| 资助信息 | 2，2 |
| 原文出处 | 7080 |
| 语种 | 英语 |
| WOS记录号 | WOS:000327506600028 |
| 公开日期 | 2014-09-11 |
| 源URL | [http://159.226.238.44/handle/321008/119098]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.E China Univ Sci & Technol, Engn Res Ctr Pharmaceut Proc Chem, Minist Educ, Sch Pharm, Shanghai 200237, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China 3.Dalian Maritime Univ, Dalian 116026, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sheng, Qianying,Li, Xiuling,Yin, Wei,et al. Retention mechanism and enrichment of glycopeptides on titanium dioxide[J]. analytical methods,2013,5(24):7072-7080. |
| APA | Sheng, Qianying,Li, Xiuling,Yin, Wei,Yu, Long,Ke, Yanxiong,&Liang, Xinmiao.(2013).Retention mechanism and enrichment of glycopeptides on titanium dioxide.analytical methods,5(24),7072-7080. |
| MLA | Sheng, Qianying,et al."Retention mechanism and enrichment of glycopeptides on titanium dioxide".analytical methods 5.24(2013):7072-7080. |
入库方式： OAI收割
来源：大连化学物理研究所
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