Microfluidic Device for Controllable Chemical Release via Field-Actuated Membrane Incorporating Nanoparticles
文献类型：期刊论文
| 作者 | Wang, Xiang1; Li, Shunbo2,3; Wang, Limu1; Yi, Xin1; Hui, Yu Sanna1; Qin, Jianhua4; Wen, Weijia1,2,3 |
| 刊名 | journal of nanomaterials
 |
| 出版日期 | 2013 |
| 卷号 | 2013页码:864584 |
| ISSN号 | 1687--4110 |
| 产权排序 | 待补充 |
| 通讯作者 | weijia wen |
| 合作状况 | 英 |
| 英文摘要 | we report a robust magnetic-membrane-based microfluidic platform for controllable chemical release. the magnetic membrane was prepared by mixing polydimethylsiloxane (pdms) and carbonyl-iron nanoparticles together to obtain a flexible thin film. with combined, simultaneous regulation of magnetic stimulus and mechanical pumping, the desired chemical release rate can easily be realized. for example, the dose release experimental data was well fitted by a mathematical sigmoidal model, exhibiting a typical dose-response relationship, which shows promise in providing significant guidance for on-demand drug delivery. to test the platform's feasibility, our microfluidic device was employed in an experiment involving escherichia coli culture under controlled antibiotic ciprofloxacin exposure, and the expected outcomes were successfully obtained. our experimental results indicate that such a microfluidic device, with high accuracy and easy manipulation properties, can legitimately be characterized as active chemical release system. |
| WOS标题词 | science & technology ; technology |
| 学科主题 | 物理化学 |
| 类目[WOS] | nanoscience & nanotechnology ; materials science, multidisciplinary |
| 研究领域[WOS] | science & technology - other topics ; materials science |
| 关键词[WOS] | drug-delivery ; microcapsules ; fabrication ; microneedles ; design |
| 收录类别 | SCI |
| 资助信息 | 3，6 |
| 原文出处 | 864584 |
| 语种 | 英语 |
| WOS记录号 | WOS:000325321100001 |
| 公开日期 | 2014-09-11 |
| 源URL | [http://159.226.238.44/handle/321008/119274]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Hong Kong Univ Sci & Technol, Nanosci & Nanotechnol Program, Kowloon, Hong Kong, Peoples R China 2.Hong Kong Univ Sci & Technol, Dept Phys, Kowloon, Hong Kong, Peoples R China 3.Hong Kong Univ Sci & Technol, KAUST HKUST Joint Micro Nanofluid Lab, Kowloon, Hong Kong, Peoples R China 4.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Xiang,Li, Shunbo,Wang, Limu,et al. Microfluidic Device for Controllable Chemical Release via Field-Actuated Membrane Incorporating Nanoparticles[J]. journal of nanomaterials,2013,2013:864584. |
| APA | Wang, Xiang.,Li, Shunbo.,Wang, Limu.,Yi, Xin.,Hui, Yu Sanna.,...&Wen, Weijia.(2013).Microfluidic Device for Controllable Chemical Release via Field-Actuated Membrane Incorporating Nanoparticles.journal of nanomaterials,2013,864584. |
| MLA | Wang, Xiang,et al."Microfluidic Device for Controllable Chemical Release via Field-Actuated Membrane Incorporating Nanoparticles".journal of nanomaterials 2013(2013):864584. |
入库方式： OAI收割
来源：大连化学物理研究所
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