Synthesis of functionalized 2-pyridones via Michael addition and cyclization reaction of amines, alkynes and dialkyl acetylene dicarboxylates
文献类型：期刊论文
| 作者 | Chong, Qinglei; Xin, Xiaoyi; Wang, Chunxiang; Wu, Fan; Wan, Boshun |
| 刊名 | rsc advances
 |
| 出版日期 | 2013 |
| 卷号 | 3期号:44页码:21222-21226 |
| 产权排序 | 待补充 |
| 通讯作者 | 万伯顺 |
| 合作状况 | 英 |
| 英文摘要 | the michael addition and three-component cyclization reaction of amines, alkynes and dialkyl acetylene dicarboxylates to form pyridones has been developed. aliphatic amines and aromatic amines could selectively be converted into n-alkyl-disubstituted 2-pyridones and n-aryl-trisubstituted 2-pyridones with good yields in the presence of wet ethanol, which means a suitable amount of water is required for this reaction. the michael addition and cyclization reaction process was confirmed through deuterium-labeling experiments, intermediates isolation and control experiments. |
| WOS标题词 | science & technology ; physical sciences |
| 学科主题 | 物理化学 |
| 类目[WOS] | chemistry, multidisciplinary |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | ring-fused 2-pyridones ; regioselective synthesis ; pyridone alkaloids ; derivatives ; mechanism ; transformations ; cycloaddition ; hydrolysis ; scaffolds ; migration |
| 收录类别 | SCI |
| 资助信息 | 1，1 |
| 原文出处 | 21226 |
| 语种 | 英语 |
| WOS记录号 | WOS:000326056600005 |
| 公开日期 | 2014-09-11 |
| 源URL | [http://159.226.238.44/handle/321008/119481]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chong, Qinglei,Xin, Xiaoyi,Wang, Chunxiang,et al. Synthesis of functionalized 2-pyridones via Michael addition and cyclization reaction of amines, alkynes and dialkyl acetylene dicarboxylates[J]. rsc advances,2013,3(44):21222-21226. |
| APA | Chong, Qinglei,Xin, Xiaoyi,Wang, Chunxiang,Wu, Fan,&Wan, Boshun.(2013).Synthesis of functionalized 2-pyridones via Michael addition and cyclization reaction of amines, alkynes and dialkyl acetylene dicarboxylates.rsc advances,3(44),21222-21226. |
| MLA | Chong, Qinglei,et al."Synthesis of functionalized 2-pyridones via Michael addition and cyclization reaction of amines, alkynes and dialkyl acetylene dicarboxylates".rsc advances 3.44(2013):21222-21226. |
入库方式： OAI收割
来源：大连化学物理研究所
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