An intelligent digital microfluidic system with fuzzy-enhanced feedback for multi-droplet manipulation
文献类型：期刊论文
| 作者 | Gao, Jie1; Liu, Xianming2; Chen, Tianlan1; Mak, Pui-In1; Du, Yuguang2; Vai, Mang-I1; Lin, Bingcheng2; Martins, Rui P.1 |
| 刊名 | lab on a chip
 |
| 出版日期 | 2013 |
| 卷号 | 13期号:3页码:443-451 |
| ISSN号 | 1473-0197 |
| 产权排序 | 待补充 |
| 通讯作者 | 林炳承 ; martins rp |
| 合作状况 | 英 |
| 英文摘要 | the complexity of droplet hydrodynamics on a digital microfluidic (dmf) system eventually weakens its potential for application in large-scale chemical/biological micro-reactors. we describe here an intelligent dmf technology to address that intricacy. a wide variety of control-engaged droplet manageability is proposed and demonstrated through the operation of our modular dmf prototype, which comprises: (i) rigid profiling ability of different droplet's hydrodynamics under a real-time trajectory track of droplet-derived capacitance, permitting accurate and autonomous multi-droplet positioning without visual setup and heavy image signal processing; (ii) fuzzy-enhanced controllability saving up to 21% charging time when compared with the classical approach, enhancing the throughput, fidelity and lifetime of the dmf chip, while identifying and renouncing those weakened electrodes deteriorated over time, and (iii) expert manipulability of multi-droplet routings under countermeasure decisions in real time, preventing droplet-to-droplet or task-to-task interference. altogether, this work exhibits the first modular dmf system with built-in electronic-control software-defined intelligence to enhance the fidelity and reliability of each droplet operation, allowing future manufacturability of a wide range of life science analyses and combinatorial chemical screening applications. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 学科主题 | 物理化学 |
| 类目[WOS] | biochemical research methods ; chemistry, multidisciplinary ; nanoscience & nanotechnology |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry ; science & technology - other topics |
| 关键词[WOS] | on-a-chip ; actuation ; biochips ; platform ; devices |
| 收录类别 | SCI |
| 资助信息 | 2，2 |
| 原文出处 | 451 |
| 语种 | 英语 |
| WOS记录号 | WOS:000312947300016 |
| 公开日期 | 2014-09-11 |
| 源URL | [http://159.226.238.44/handle/321008/119592]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Univ Macau, State Key Lab Analog & Mixed Signal VLSI & FST EC, Taipa, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Res Ctr Lab Chip, Dalian, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gao, Jie,Liu, Xianming,Chen, Tianlan,et al. An intelligent digital microfluidic system with fuzzy-enhanced feedback for multi-droplet manipulation[J]. lab on a chip,2013,13(3):443-451. |
| APA | Gao, Jie.,Liu, Xianming.,Chen, Tianlan.,Mak, Pui-In.,Du, Yuguang.,...&Martins, Rui P..(2013).An intelligent digital microfluidic system with fuzzy-enhanced feedback for multi-droplet manipulation.lab on a chip,13(3),443-451. |
| MLA | Gao, Jie,et al."An intelligent digital microfluidic system with fuzzy-enhanced feedback for multi-droplet manipulation".lab on a chip 13.3(2013):443-451. |
入库方式： OAI收割
来源：大连化学物理研究所
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