A dextran-bonded stationary phase for saccharide separation
文献类型：期刊论文
| 作者 | Sheng, Qianying1; Su, Xindai3; Li, Xiuling2; Ke, Yanxiong1; Liang, Xinmiao1,2 |
| 刊名 | journal of chromatography a
 |
| 出版日期 | 2014-06-06 |
| 卷号 | 1345页码:57-67 |
| 关键词 | Dextran Oligosaccharide Glycopeptides HILIC MS |
| ISSN号 | 0021-9673 |
| 产权排序 | 待补充 |
| 通讯作者 | 柯燕雄 ; 梁鑫淼 |
| 合作状况 | 英 |
| 英文摘要 | a-saccharide-based stationary phase for hydrophilic interaction liquid chromatography (hilic) is presented. the method uses carbonyl di-imidazole (cdi) as a cross-linker for dextran in aqueous solution. different from the traditional immobilized saccharide stationary phase, this method was using a simple way to bond the high molecular of polysaccharide immobilized on the silica gel. the new method avoided the time-consuming process but had a very considerable loading result. with silica-based surface bonded, it will be possible to develop well-defined surface modifications that promote the hydrophilic with dextran and high mechanical strength with silica. for all tested compounds, including polar compounds and carbohydrates, this dextran-bonded stationary phase performed well in terms of separation efficiency and column stability, and the retention mechanism matched that of typical hilic retention. moreover, good selectivity was achieved in the separation of oligosaccharides and glycopeptides. (c) 2014 elsevier b.v. all rights reserved. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 学科主题 | 物理化学 |
| 类目[WOS] | biochemical research methods ; chemistry, analytical |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry |
| 关键词[WOS] | hydrophilic-interaction chromatography ; interaction liquid-chromatography ; light-scattering detection ; mass-spectrometry ; reversed-phase ; panax-notoginseng ; peptide synthesis ; polar compounds ; silica ; glycopeptides |
| 收录类别 | SCI |
| 资助信息 | 2，3 |
| 原文出处 | 67 |
| 语种 | 英语 |
| WOS记录号 | WOS:000336709300008 |
| 公开日期 | 2014-09-11 |
| 源URL | [http://159.226.238.44/handle/321008/119817]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.E China Univ Sci & Technol, Sch Pharm, Engn Res Ctr Pharmaceut Proc Chem, Minist Educ, Shanghai 200237, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China 3.Dalian Med Univ, Affiliated Hosp 2, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sheng, Qianying,Su, Xindai,Li, Xiuling,et al. A dextran-bonded stationary phase for saccharide separation[J]. journal of chromatography a,2014,1345:57-67. |
| APA | Sheng, Qianying,Su, Xindai,Li, Xiuling,Ke, Yanxiong,&Liang, Xinmiao.(2014).A dextran-bonded stationary phase for saccharide separation.journal of chromatography a,1345,57-67. |
| MLA | Sheng, Qianying,et al."A dextran-bonded stationary phase for saccharide separation".journal of chromatography a 1345(2014):57-67. |
入库方式： OAI收割
来源：大连化学物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。