The Studies on Pharmacophore Model of K+ Channel Opener
文献类型：期刊论文
| 作者 | Chen Hongming; Zhou Jiaju; Xie Guirong; Pang Suhua |
| 刊名 | ACTA PHYSICO-CHIMICA SINICA
 |
| 出版日期 | 1997 |
| 卷号 | 13期号:2页码:101-105 |
| 关键词 | K+ channel opener CoMFA Pharmacophore model QSAR |
| ISSN号 | 1000-6818 |
| 其他题名 | Acta Phys.-Chim. Sin. |
| 中文摘要 | In this paper, a set of ATP sensitive K+ channel openers (KCO) whose structure are different, were investigated with the aim to develope our previously defined KCO's pharmacophore model.To validate the effectiveness of the pharmacophore model, A Comparative molecule field analysis (CoMFA) was proceeded, aligning the molecules according to the requirement of the model, and good results were obtained. This pharmacophore model may be a start point to design new KCO compounds. |
| 英文摘要 | In this paper, a set of ATP sensitive K+ channel openers (KCO) whose structure are different, were investigated with the aim to develope our previously defined KCO's pharmacophore model.To validate the effectiveness of the pharmacophore model, A Comparative molecule field analysis (CoMFA) was proceeded, aligning the molecules according to the requirement of the model, and good results were obtained. This pharmacophore model may be a start point to design new KCO compounds. |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 类目[WOS] | Chemistry, Physical |
| 研究领域[WOS] | Chemistry |
| 收录类别 | SCI |
| 原文出处 | |
| 语种 | 英语 |
| WOS记录号 | WOS:000207601200002 |
| 公开日期 | 2014-09-30 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/11346]  |
| 专题 | 过程工程研究所_研究所（批量导入） |
| 作者单位 | Chinese Acad Sci, Inst Chem Met, Lab Comp Chemostry, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen Hongming,Zhou Jiaju,Xie Guirong,et al. The Studies on Pharmacophore Model of K+ Channel Opener[J]. ACTA PHYSICO-CHIMICA SINICA,1997,13(2):101-105. |
| APA | Chen Hongming,Zhou Jiaju,Xie Guirong,&Pang Suhua.(1997).The Studies on Pharmacophore Model of K+ Channel Opener.ACTA PHYSICO-CHIMICA SINICA,13(2),101-105. |
| MLA | Chen Hongming,et al."The Studies on Pharmacophore Model of K+ Channel Opener".ACTA PHYSICO-CHIMICA SINICA 13.2(1997):101-105. |
入库方式： OAI收割
来源：过程工程研究所
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