Biotechnological production and applications of microbial phenylalanine ammonia lyase: a recent review
文献类型：期刊论文
| 作者 | Cui, Jian Dong1,2,3; Qiu, Ji Qing4; Fan, Xian Wei5; Jia, Shi Ru3; Tan, Zhi Lei3 |
| 刊名 | CRITICAL REVIEWS IN BIOTECHNOLOGY
 |
| 出版日期 | 2014-09-01 |
| 卷号 | 34期号:3页码:258-268 |
| 关键词 | Activity applications biotechnological production microbe phenylalanine ammonia lyase purification stability |
| ISSN号 | 0738-8551 |
| 其他题名 | Crit. Rev. Biotechnol. |
| 中文摘要 | Phenylalanine ammonia lyase (PAL) catalyzes the nonoxidative deamination of L-phenylalanine to form trans-cinnamic acid and a free ammonium ion. It plays a major role in the catabolism of L-phenylalanine. The presence of PAL has been reported in diverse plants, some fungi, Streptomyces and few Cyanobacteria. In the past two decades, PAL has gained considerable significance in several clinical, industrial and biotechnological applications. Since its discovery, much knowledge has been gathered with reference to the enzyme's importance in phenyl propanoid pathway of plants. In contrast, there is little knowledge about microbial PAL. Furthermore, the commercial source of the enzyme has been mainly obtained from the fungi. This study focuses on the recent advances on the physiological role of microbial PAL and the improvements of PAL biotechnological production both from our laboratory and many others as well as the latest advances on the new applications of microbial PAL. |
| 英文摘要 | Phenylalanine ammonia lyase (PAL) catalyzes the nonoxidative deamination of L-phenylalanine to form trans-cinnamic acid and a free ammonium ion. It plays a major role in the catabolism of L-phenylalanine. The presence of PAL has been reported in diverse plants, some fungi, Streptomyces and few Cyanobacteria. In the past two decades, PAL has gained considerable significance in several clinical, industrial and biotechnological applications. Since its discovery, much knowledge has been gathered with reference to the enzyme's importance in phenyl propanoid pathway of plants. In contrast, there is little knowledge about microbial PAL. Furthermore, the commercial source of the enzyme has been mainly obtained from the fungi. This study focuses on the recent advances on the physiological role of microbial PAL and the improvements of PAL biotechnological production both from our laboratory and many others as well as the latest advances on the new applications of microbial PAL. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Biotechnology & Applied Microbiology |
| 研究领域[WOS] | Biotechnology & Applied Microbiology |
| 关键词[WOS] | TRANS-CINNAMIC ACID ; P-HYDROXYCINNAMIC ACID ; HIGH-LEVEL EXPRESSION ; RHODOTORULA-GLUTINIS ; RHODOSPORIDIUM-TORULOIDES ; ESCHERICHIA-COLI ; SACCHAROMYCES-CEREVISIAE ; BIOCHEMICAL-CHARACTERIZATION ; SPORIDIOBOLUS-PARAROSEUS ; SUBSTRATE-SPECIFICITY |
| 收录类别 | SCI |
| 原文出处 | |
| 语种 | 英语 |
| WOS记录号 | WOS:000340769000005 |
| 公开日期 | 2014-09-30 |
| 版本 | 出版稿 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/11357]  |
| 专题 | 过程工程研究所_研究所（批量导入） |
| 作者单位 | 1.Hebei Univ Sci & Technol, Res Ctr Fermentat Engn Hebei, Coll Biosci & Bioengn, Shijiazhuang 050018, Peoples R China 2.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing, Peoples R China 3.Tianjin Univ Sci & Technol, Minist Educ, Key Lab Ind Microbiol, Tianjin, Peoples R China 4.Hebei Univ Sci & Technol, Sch Sci, Shijiazhuang, Peoples R China 5.Guangxi Univ, State Key Lab Conservat & Utilizat Subtrop Agrobi, Nanning 530004, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cui, Jian Dong,Qiu, Ji Qing,Fan, Xian Wei,et al. Biotechnological production and applications of microbial phenylalanine ammonia lyase: a recent review[J]. CRITICAL REVIEWS IN BIOTECHNOLOGY,2014,34(3):258-268. |
| APA | Cui, Jian Dong,Qiu, Ji Qing,Fan, Xian Wei,Jia, Shi Ru,&Tan, Zhi Lei.(2014).Biotechnological production and applications of microbial phenylalanine ammonia lyase: a recent review.CRITICAL REVIEWS IN BIOTECHNOLOGY,34(3),258-268. |
| MLA | Cui, Jian Dong,et al."Biotechnological production and applications of microbial phenylalanine ammonia lyase: a recent review".CRITICAL REVIEWS IN BIOTECHNOLOGY 34.3(2014):258-268. |
入库方式： OAI收割
来源：过程工程研究所
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