Improving the lactic acid production of Actinobacillus succinogenes by using a novel fermentation and separation integration system
文献类型：期刊论文
| 作者 | Wang, Caixia1,2; Li, Qiang1; Wang, Dan3; Xing, Jianmin1 |
| 刊名 | PROCESS BIOCHEMISTRY
 |
| 出版日期 | 2014-08-01 |
| 卷号 | 49期号:8页码:1245-1250 |
| 关键词 | Lactic acid Actinobacillus succinogenes Membrane filtration Adsorptive separation Process integration |
| ISSN号 | 1359-5113 |
| 其他题名 | Process Biochem. |
| 中文摘要 | This work describes the development of a novel integrated system for lactic acid production by Actinobacillus succinogenes. Fermentation and separation were integrated with the use of a microfiltration (MF) membrane, and lactic acid was recovered by resin adsorption following MF. The fermentation broth containing residual sugar and nutrients was then recycled back into the fermenter after lactic acid adsorption. This novel approach overcame the problem of product inhibition and extended the cell growth period from 41 h to 120 h. Production of lactic acid was improved by 23% to 183.4 g L-1. The overall yield and productivity for glucose were 0.97 g g(-1) and 1.53 g L-1 h(-1), respectively. These experimental results indicate that the integrated system could benefit continuous production of lactic acid at high levels. (C) 2014 Elsevier Ltd. All rights reserved. |
| 英文摘要 | This work describes the development of a novel integrated system for lactic acid production by Actinobacillus succinogenes. Fermentation and separation were integrated with the use of a microfiltration (MF) membrane, and lactic acid was recovered by resin adsorption following MF. The fermentation broth containing residual sugar and nutrients was then recycled back into the fermenter after lactic acid adsorption. This novel approach overcame the problem of product inhibition and extended the cell growth period from 41 h to 120 h. Production of lactic acid was improved by 23% to 183.4 g L-1. The overall yield and productivity for glucose were 0.97 g g(-1) and 1.53 g L-1 h(-1), respectively. These experimental results indicate that the integrated system could benefit continuous production of lactic acid at high levels. (C) 2014 Elsevier Ltd. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Technology |
| 类目[WOS] | Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Engineering, Chemical |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Engineering |
| 关键词[WOS] | SUCCINIC-ACID ; BROTH ; PURIFICATION ; BIOREACTOR ; ADSORPTION ; XYLOSE ; YIELD |
| 收录类别 | SCI |
| 原文出处 | |
| 语种 | 英语 |
| WOS记录号 | WOS:000340331900005 |
| 公开日期 | 2014-09-30 |
| 版本 | 出版稿 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/11529]  |
| 专题 | 过程工程研究所_研究所（批量导入） |
| 作者单位 | 1.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Chongqing Univ, Coll Chem & Chem Engn, Chongqing 400044, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Caixia,Li, Qiang,Wang, Dan,et al. Improving the lactic acid production of Actinobacillus succinogenes by using a novel fermentation and separation integration system[J]. PROCESS BIOCHEMISTRY,2014,49(8):1245-1250. |
| APA | Wang, Caixia,Li, Qiang,Wang, Dan,&Xing, Jianmin.(2014).Improving the lactic acid production of Actinobacillus succinogenes by using a novel fermentation and separation integration system.PROCESS BIOCHEMISTRY,49(8),1245-1250. |
| MLA | Wang, Caixia,et al."Improving the lactic acid production of Actinobacillus succinogenes by using a novel fermentation and separation integration system".PROCESS BIOCHEMISTRY 49.8(2014):1245-1250. |
入库方式： OAI收割
来源：过程工程研究所
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