Antimicrobial Constituents of the Mature Carpels of Manglietiastrum sinicum
文献类型：期刊论文
| 作者 | Ding, Jia-Yin1,2; Yuan, Chun-Mao1; Cao, Ming-Ming1; Liu, Wei-Wei1; Yu, Chun1; Zhang, Hai-Yuan1; Zhang, Yu1 ; Di, Ying-Tong1; He, Hong-Ping1; Li, Shun-Lin1
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| 刊名 | JOURNAL OF NATURAL PRODUCTS
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| 出版日期 | 2014-08-01 |
| 卷号 | 77期号:8页码:1800-1805 |
| ISSN号 | 0163-3864 |
| 关键词 | ABSOLUTE-CONFIGURATION LIGNANS TETRAHYDROFURAN AGGREGATION INHIBITION CHINENSIS PLANTS STEM |
| 通讯作者 | Li, SL (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China. ; lisl@mail.kib.ac.cn ; haoxj@mail.kib.ac.cn |
| 产权排序 | 第一 |
| 英文摘要 | Seven new compounds, including a eupodienone-type lignan (1), a dibenzocyclooctadiene-type lignan (2), three tetrahydrofuran-type lignans (3-5), and two 1-phenyl-butyl benzoates (6, 7), together with six known compounds, were isolated from the mature carpels of Manglietiastrum sinicum. The structures of new compounds 1-7 were defined by spectroscopic techniques, and the absolute configuration of manglisin A (1) was determined by X-ray crystallography. Compounds 1-4 exhibited moderate antimicrobial activities (MIC values: 0.016-0.14 mu M) against Staphylococcus aureus, MRSA 82(#), MESA 92(#), NLRSA 98(#), and MRSA 331(#). Compounds 2 and 3 showed weak cytotoxic activity against five human tumor cell lines. |
| 学科主题 | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 类目[WOS] | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Plant Sciences ; Pharmacology & Pharmacy |
| 关键词[WOS] | ABSOLUTE-CONFIGURATION ; LIGNANS ; TETRAHYDROFURAN ; AGGREGATION ; INHIBITION ; CHINENSIS ; PLANTS ; STEM |
| 资助信息 | National Natural Science Foundation of China [31270404] |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000340861800006 |
| 公开日期 | 2014-10-11 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/18253]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ding, Jia-Yin,Yuan, Chun-Mao,Cao, Ming-Ming,et al. Antimicrobial Constituents of the Mature Carpels of Manglietiastrum sinicum[J]. JOURNAL OF NATURAL PRODUCTS,2014,77(8):1800-1805. |
| APA | Ding, Jia-Yin.,Yuan, Chun-Mao.,Cao, Ming-Ming.,Liu, Wei-Wei.,Yu, Chun.,...&Hao, Xiao-Jiang.(2014).Antimicrobial Constituents of the Mature Carpels of Manglietiastrum sinicum.JOURNAL OF NATURAL PRODUCTS,77(8),1800-1805. |
| MLA | Ding, Jia-Yin,et al."Antimicrobial Constituents of the Mature Carpels of Manglietiastrum sinicum".JOURNAL OF NATURAL PRODUCTS 77.8(2014):1800-1805. |
入库方式： OAI收割
来源：昆明植物研究所
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