Structure and cytotoxic evaluation of five 12-oxygenated eremophilanes from Ligularia lingiana
文献类型：期刊论文
| 作者 | Saito, Yoshinori1; Sasaki, Yoko1; Komiyama, Teppei2; Ohsaki, Ayumi2; Okamoto, Yasuko1; Gong, Xun3 ; Kuroda, Chiaki4,5; Tori, Motoo1
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| 刊名 | TETRAHEDRON
 |
| 出版日期 | 2014-09-02 |
| 卷号 | 70期号:35页码:5878-5883 |
| 关键词 | Asteraceae Ligularia lingiana Sesquiterpenoid Eremophilane Dimer |
| ISSN号 | 0040-4020 |
| 产权排序 | 第三 |
| 通讯作者 | Gong, X (reprint author), Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China. ; gongxun@mail.kib.ac.cn ; chkkuroda@rikkyo.ac.jp ; tori@ph.bunri-u.ac.jp |
| 英文摘要 | Five new 12-oxygenated eremophilane sesquiterpenoids bearing a B-ring enone system were isolated from Ligularia lingiana S.W. Liu (Asteraceae) collected in China. Compound 5 was a Diels-Alder adduct of 3 alpha-angeloyloxy-7 beta H-8-oxoeremophila-9,11(13)-dien-12-al and the monoterpene, ocimene. Compound I showed cytotoxic activities against HeLa, HL60, Jurkat, and NIH-3T3 cells at IC50 0.0407, 0.440, 0.313, and 3.48 mu M, respectively. (C) 2014 Elsevier Ltd. All rights reserved. |
| 学科主题 | Chemistry, Organic |
| 类目[WOS] | Chemistry, Organic |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | HYBRIDUS L GM ; GENETIC DIVERSITY ; CHEMICAL-CONSTITUENTS ; PETASITES COMPONENTS ; SOUTHWESTERN SICHUAN ; HENGDUAN MOUNTAINS ; YUNNAN PROVINCE ; CHINA ; DERIVATIVES ; SESQUITERPENES |
| 收录类别 | SCI ; IC |
| 资助信息 | Japan Society for the Promotion of Science [21404009] |
| 语种 | 英语 |
| WOS记录号 | WOS:000340336000064 |
| 公开日期 | 2014-10-11 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/18306]  |
| 专题 | 昆明植物研究所_资源植物与生物技术所级重点实验室 |
| 作者单位 | 1.Tokushima Bunri Univ, Fac Pharmaceut Sci, Yamashiro, Tokushima 7708514, Japan 2.Tokyo Med & Dent Univ, Inst Biomat & Bioengn, Chiyoda Ku, Tokyo 1010062, Japan 3.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China 4.Rikkyo Univ, Dept Chem, Toshima Ku, Tokyo 1718501, Japan 5.Rikkyo Univ, Res Ctr Smart Mol, Toshima Ku, Tokyo 1718501, Japan |
| 推荐引用方式 GB/T 7714 | Saito, Yoshinori,Sasaki, Yoko,Komiyama, Teppei,et al. Structure and cytotoxic evaluation of five 12-oxygenated eremophilanes from Ligularia lingiana[J]. TETRAHEDRON,2014,70(35):5878-5883. |
| APA | Saito, Yoshinori.,Sasaki, Yoko.,Komiyama, Teppei.,Ohsaki, Ayumi.,Okamoto, Yasuko.,...&Tori, Motoo.(2014).Structure and cytotoxic evaluation of five 12-oxygenated eremophilanes from Ligularia lingiana.TETRAHEDRON,70(35),5878-5883. |
| MLA | Saito, Yoshinori,et al."Structure and cytotoxic evaluation of five 12-oxygenated eremophilanes from Ligularia lingiana".TETRAHEDRON 70.35(2014):5878-5883. |
入库方式： OAI收割
来源：昆明植物研究所
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