DNA display for drug discovery
文献类型：期刊论文
| 作者 | Chen, Haodong ; Chen, Gangyi ; Du, Feng ; Fu, Qingquan ; Zhao, Yun ; Tang, Zhuo |
| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2013 |
| 卷号 | 3期号:37页码:16251-16254 |
| ISSN号 | 2046-2069 |
| 产权排序 | 1 |
| 通讯作者 | Tang, Z (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, Chengdu 610041, Peoples R China. |
| 英文摘要 | A novel DNA display strategy, based on a new puromycin modifier, has been developed. The 5'-end puromycin-tethered oligonucleotide was synthesized to hybridize with mRNA, so that it could attack the nascent polypeptides during in vitro translation. The DNA-peptide fusion molecule can tolerate more harsh and stringent selection conditions, therefore, this DNA display may become a useful tool for in vitro display technologies for the selection of peptide drug candidates. |
| 学科主题 | Chemistry |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000323842900005 |
| 公开日期 | 2014-11-21 |
| 源URL | [http://210.75.237.14/handle/351003/24185]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 推荐引用方式 GB/T 7714 | Chen, Haodong,Chen, Gangyi,Du, Feng,et al. DNA display for drug discovery[J]. RSC ADVANCES,2013,3(37):16251-16254. |
| APA | Chen, Haodong,Chen, Gangyi,Du, Feng,Fu, Qingquan,Zhao, Yun,&Tang, Zhuo.(2013).DNA display for drug discovery.RSC ADVANCES,3(37),16251-16254. |
| MLA | Chen, Haodong,et al."DNA display for drug discovery".RSC ADVANCES 3.37(2013):16251-16254. |
入库方式： OAI收割
来源：成都生物研究所
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