L-Pipecolinic acid derived Lewis base organocatalyst for asymmetric reduction of N-aryl imines by trichlorosilane: effects of the side amide group on catalytic performances
文献类型：期刊论文
| 作者 | Wang, Zhouyu ; Wang, Chao ; Zhou, Li ; Sun, Jian |
| 刊名 | ORGANIC & BIOMOLECULAR CHEMISTRY
 |
| 出版日期 | 2013 |
| 卷号 | 11期号:5页码:787-797 |
| ISSN号 | 1477-0520 |
| 产权排序 | 2 |
| 通讯作者 | Wang, ZY (reprint author), Xihua Univ, Dept Pharmaceut Engn, Chengdu, Peoples R China ; Sun, Jian |
| 英文摘要 | A series of N-formamides derived from pipecolinic acid have been synthesized and tested as Lewis base catalysts for the enantioselective reduction of N-aryl imines by trichlorosilane. Through the investigation of the structure-efficacy relationship between the side amide group and catalytic performance, several highly effective catalysts were discovered. In particular, arylamido-type catalyst 5i and non-arylamido-type catalyst 6c exhibited high reactivity and enantioselectivity, furnishing the reduction of a wide variety of N-aryl imines with high isolated yields (up to 98%) and ee values (up to 96%) under mild conditions. Moreover, these two catalysts complement each other in terms of their tolerances to nonaromatic ketimines and non-methyl ketimines. |
| 学科主题 | Chemistry |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000312946200012 |
| 公开日期 | 2014-11-21 |
| 源URL | [http://210.75.237.14/handle/351003/24195]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 推荐引用方式 GB/T 7714 | Wang, Zhouyu,Wang, Chao,Zhou, Li,et al. L-Pipecolinic acid derived Lewis base organocatalyst for asymmetric reduction of N-aryl imines by trichlorosilane: effects of the side amide group on catalytic performances[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2013,11(5):787-797. |
| APA | Wang, Zhouyu,Wang, Chao,Zhou, Li,&Sun, Jian.(2013).L-Pipecolinic acid derived Lewis base organocatalyst for asymmetric reduction of N-aryl imines by trichlorosilane: effects of the side amide group on catalytic performances.ORGANIC & BIOMOLECULAR CHEMISTRY,11(5),787-797. |
| MLA | Wang, Zhouyu,et al."L-Pipecolinic acid derived Lewis base organocatalyst for asymmetric reduction of N-aryl imines by trichlorosilane: effects of the side amide group on catalytic performances".ORGANIC & BIOMOLECULAR CHEMISTRY 11.5(2013):787-797. |
入库方式： OAI收割
来源：成都生物研究所
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