中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 成都生物研究所
  3. 中国科学院成都生物研究所
  4. 天然产物研究
Daphniphyllum Alkaloids: Recent Findings on Chemistry and Pharmacology

文献类型：期刊论文

作者Wu, HF ; Zhang, XP ; Ding, LS ; Chen, SL ; Yang, JS ; Xu, XD
刊名PLANTA MEDICA
出版日期2013
卷号79期号:17页码:1589-1598
关键词Daphniphyllum Daphniphyllaceae alkaloids synthesis biological activity
ISSN号0032-0943
产权排序2
通讯作者Xu, XD
中文摘要The unique polycyclic fused ring systems of Daphniphyllum alkaloids, along with their extensive bioactivities, make this family of alkaloids especially attractive targets for total synthesis and biogenetic studies. Successive discoveries of new alkaloids with unprecedented skeletons have made a great contribution to structural diversities of alkaloids elaborated by plants of the genus Daphniphyllum. By the end of 2008, more than 200 alkaloids belonging to 14 different skeletal types have been isolated from different parts of plants of thirteen Daphniphyllum species. These alkaloids show cytotoxic, antioxidant, vasorelaxant, and antiplatelet activating factor effects. The plausible biosynthetic pathways for Daphniphyllum alkaloids have been proposed and biomimetic total syntheses of some alkaloids completed. To provide an update of the previous reviews published in 2009, new structures, synthesis, and bioactivity of Daphniphyllum alkaloids reported in recent years are presented in this article. In the meantime, an additional 54 novel alkaloids have been isolated and identified. Among them, some possess unprecedented frameworks. Several inspired organic syntheses were completed.
学科主题Plant Sciences;Pharmacology & Pharmacy
收录类别SCI
语种英语
WOS记录号WOS:000327472000001
公开日期2014-11-21
源URL[http://210.75.237.14/handle/351003/24204]  
专题成都生物研究所_天然产物研究
推荐引用方式
GB/T 7714		 Wu, HF,Zhang, XP,Ding, LS,et al. Daphniphyllum Alkaloids: Recent Findings on Chemistry and Pharmacology[J]. PLANTA MEDICA,2013,79(17):1589-1598.
APA Wu, HF,Zhang, XP,Ding, LS,Chen, SL,Yang, JS,&Xu, XD.(2013).Daphniphyllum Alkaloids: Recent Findings on Chemistry and Pharmacology.PLANTA MEDICA,79(17),1589-1598.
MLA Wu, HF,et al."Daphniphyllum Alkaloids: Recent Findings on Chemistry and Pharmacology".PLANTA MEDICA 79.17(2013):1589-1598.

入库方式： OAI收割

来源：成都生物研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。