Highly Efficient Synthesis of Two Globo H Tetrasaccharide Analogues
文献类型：期刊论文
| 作者 | Wei Guo-Hua ; Du Yu-Guo ; Matta, Khushi L. |
| 刊名 | CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
 |
| 出版日期 | 2012 |
| 卷号 | 33期号:1页码:71－75 |
| 关键词 | Globo H Glycosyltransferase Sulfotransferase Glucuronic acid 2-Naphthylmethyl |
| ISSN号 | 0251-0790 |
| 中文摘要 | The synthesis of two Globo H tetrasaccharide analogues, allyl O-(beta-D-glucopyranosyluronic acid) ( 1,3)-O-(beta-D-galactopyranosyl)-(1, 3)-(2-acetamido-2-deoxy-beta-D-galactopyranosyl)-(1, 3)-O-alpha-D-galactopyranoside and allyl O-(3-O-sulfo-beta-D-glucopyranosyluronic acid)-(1, 3)-O-(beta-D-galactopyranosyl)-(1, 3)-(2-acetamido-2-deoxy-beta-D-galactopyranosyl)-(1,3)-O-alpha-D-galactopyranoside, were described. Construction of the target molecules was achieved through a key combination of BF3 center dot Et2O and trichloroacetimidate glycosylation methodology. This is the first report on the synthesis of these derivatives, which could be used as potential novel substrates and reference samples for the study of beta 1,3-glucuronosyltransferase and GlcA-3-O-sulfotransferase in cancer tissues. |
| WOS记录号 | WOS:000299715900012 |
| 公开日期 | 2014-11-04 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/7777]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Wei Guo-Hua,Du Yu-Guo,Matta, Khushi L.. Highly Efficient Synthesis of Two Globo H Tetrasaccharide Analogues[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2012,33(1):71－75. |
| APA | Wei Guo-Hua,Du Yu-Guo,&Matta, Khushi L..(2012).Highly Efficient Synthesis of Two Globo H Tetrasaccharide Analogues.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,33(1),71－75. |
| MLA | Wei Guo-Hua,et al."Highly Efficient Synthesis of Two Globo H Tetrasaccharide Analogues".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 33.1(2012):71－75. |
入库方式： OAI收割
来源：生态环境研究中心
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