Immunological detection of hepatocellular carcinoma biomarker GP73 based on dissolved magnetic nanoparticles
文献类型：期刊论文
| 作者 | Yang, Mingzhu1; Guan, Yueping1; Yang, Yu2; Xie, Li3; Xia, Tingting1; Xiong, Wubin1; Guo, Chen4 |
| 刊名 | COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
 |
| 出版日期 | 2014-02-20 |
| 卷号 | 443期号:FEB.页码:280-285 |
| 关键词 | Magnetic nanoparticles GP73 Immunoassay |
| ISSN号 | 0927-7757 |
| 其他题名 | Colloid Surf. A-Physicochem. Eng. Asp. |
| 中文摘要 | The peroxidase-like activity of dissolved Fe3O4 magnetic nanoparticles was reported in this work. The chromogenic results of dissolved magnetic nanoparticles demonstrated almost the same change trend as standard ferric ion solutions. And the chromogenic reactions of dissolved Fe3O4 magnetic nanoparticles were more sensitive than that of whole Fe3O4 magnetic nanoparticles. The chromogenic reaction of dissolved Fe3O4 magnetic nanoparticles was utilized to replace the chromogenic reaction of horseradish peroxidase in traditional enzyme-linked immunosorbent assay and applied in the immunoassay of hepatocellular carcinoma biomarker GP73. The method based on the chromogenic reaction of dissolved Fe3O4 magnetic nanoparticles achieved a detection limit of 250 ng/mL, which was more sensitive than the method based on the peroxidase-like activity of whole Fe3O4 magnetic nanoparticles. The immunological detection method based on dissolved Fe3O4 magnetic nanoparticles proved to be simple, sensitive, specific and low-cost in this paper. (C) 2013 Elsevier B.V. All rights reserved. |
| 英文摘要 | The peroxidase-like activity of dissolved Fe3O4 magnetic nanoparticles was reported in this work. The chromogenic results of dissolved magnetic nanoparticles demonstrated almost the same change trend as standard ferric ion solutions. And the chromogenic reactions of dissolved Fe3O4 magnetic nanoparticles were more sensitive than that of whole Fe3O4 magnetic nanoparticles. The chromogenic reaction of dissolved Fe3O4 magnetic nanoparticles was utilized to replace the chromogenic reaction of horseradish peroxidase in traditional enzyme-linked immunosorbent assay and applied in the immunoassay of hepatocellular carcinoma biomarker GP73. The method based on the chromogenic reaction of dissolved Fe3O4 magnetic nanoparticles achieved a detection limit of 250 ng/mL, which was more sensitive than the method based on the peroxidase-like activity of whole Fe3O4 magnetic nanoparticles. The immunological detection method based on dissolved Fe3O4 magnetic nanoparticles proved to be simple, sensitive, specific and low-cost in this paper. (C) 2013 Elsevier B.V. All rights reserved. |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 类目[WOS] | Chemistry, Physical |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | PEROXIDASE-LIKE ACTIVITY ; SENSITIVE DETECTION ; HYDROGEN-PEROXIDE ; IMMUNOASSAY ; ASSAY ; SERUM |
| 收录类别 | SCI |
| 原文出处 | |
| 语种 | 英语 |
| WOS记录号 | WOS:000342501300039 |
| 公开日期 | 2014-11-02 |
| 版本 | 出版稿 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/11661]  |
| 专题 | 过程工程研究所_研究所（批量导入） |
| 作者单位 | 1.Univ Sci & Technol Beijing, Sch Mat Sci & Engn, Beijing 100083, Peoples R China 2.China Acad Inspect & Quarantine, Beijing 100123, Peoples R China 3.Capital Med Univ, Beijing Youan Hosp, Beijing 100054, Peoples R China 4.Chinese Acad Sci, Inst Proc Engn, Lab Separat Sci & Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Mingzhu,Guan, Yueping,Yang, Yu,et al. Immunological detection of hepatocellular carcinoma biomarker GP73 based on dissolved magnetic nanoparticles[J]. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,2014,443(FEB.):280-285. |
| APA | Yang, Mingzhu.,Guan, Yueping.,Yang, Yu.,Xie, Li.,Xia, Tingting.,...&Guo, Chen.(2014).Immunological detection of hepatocellular carcinoma biomarker GP73 based on dissolved magnetic nanoparticles.COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,443(FEB.),280-285. |
| MLA | Yang, Mingzhu,et al."Immunological detection of hepatocellular carcinoma biomarker GP73 based on dissolved magnetic nanoparticles".COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS 443.FEB.(2014):280-285. |
入库方式： OAI收割
来源：过程工程研究所
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