De Novo Design, Synthesis and Evaluation of Benzylpiperazine Derivatives as Highly Selective Binders of Mcl-1
文献类型：期刊论文
| 作者 | Ding X(丁晓) ; Li Y(李嫣) ; Lv L(吕丽) ; Zhou M(周宓) ; Han L(韩莉) ; Zhang ZX(张政希) ; Li JQ(李井泉) ; Wang H(王辉) ; Liu H(柳红) ; Wang RX(王任小) |
| 刊名 | ChemMedChem
 |
| 出版日期 | 2013 |
| 卷号 | 8期号:12页码:1986-2014 |
| ISSN号 | 1860-7179 |
| 其他题名 | 从头设计, 合成和评价高选择性Mcl-1抑制剂苄基哌嗪类衍生物 |
| 通讯作者 | 柳红 ; 王任小 |
| 英文摘要 | Considerable efforts have been made to the development of small-molecule inhibitors of antiapoptotic B-cell lymphoma2 (Bcl-2) family proteins (such as Bcl-2, Bcl-x(L), and Mcl-1) as a new class of anticancer therapies. Unlike general inhibitors of the ent |
| 学科主题 | 有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1002/cmdc.201300316 |
| 语种 | 英语 |
| WOS记录号 | WOS:000327504400009 |
| 公开日期 | 2014-12-08 |
| 源URL | [http://ir.sioc.ac.cn/handle/331003/29463]  |
| 专题 | 上海有机化学研究所_计算机化学与化学信息学研究室 |
| 推荐引用方式 GB/T 7714 | Ding X,Li Y,Lv L,et al. De Novo Design, Synthesis and Evaluation of Benzylpiperazine Derivatives as Highly Selective Binders of Mcl-1[J]. ChemMedChem,2013,8(12):1986-2014. |
| APA | 丁晓.,李嫣.,吕丽.,周宓.,韩莉.,...&王任小.(2013).De Novo Design, Synthesis and Evaluation of Benzylpiperazine Derivatives as Highly Selective Binders of Mcl-1.ChemMedChem,8(12),1986-2014. |
| MLA | 丁晓,et al."De Novo Design, Synthesis and Evaluation of Benzylpiperazine Derivatives as Highly Selective Binders of Mcl-1".ChemMedChem 8.12(2013):1986-2014. |
入库方式： OAI收割
来源：上海有机化学研究所
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