New anti-infective cycloheptadepsipeptide congeners and absolute stereochemistry from the deep sea-derived Streptomyces drozdowiczii SCSIO 10141
文献类型：期刊论文
| 作者 | Zhou, X ; Huang, HB ; Li, J ; Song, YX ; Jiang, RW ; Liu, J ; Zhang, S ; Hua, Y ; Ju, JH |
| 刊名 | TETRAHEDRON
 |
| 出版日期 | 2014 |
| 卷号 | 70期号:42页码:7795-7801 |
| 关键词 | Cycloheptapeptide Streptomyces drozdowiczii Anti-infective Marine-derived actinomycete Marformycins A-F |
| ISSN号 | 0040-4020 |
| 通讯作者 | huayan@mail.kib.ac.cn ; jju@scsio.ac.cn |
| 中文摘要 | Six cycloheptadepsipeptides, marformycins A-F (1-6), featuring a unique N-terminally formylated side chain and five non-proteinogenic amino acid residues, were isolated from the deep Sea-derived Streptomyces drozdowiczii SCSIO 10141. The previously unsolved absolute stereochemistry of 3 and 4 was determined and the structures of other four new congeners were elucidated by extensive spectroscopic, chiral-phase HPLC, and single-crystal X-ray diffraction analyses. Compounds 1-5 bear no cytotoxicity against a number of human tumor cell lines but show selective anti-infective activity against Micrococcus luteus. (C) 2014 Elsevier Ltd. All rights reserved. |
| 学科主题 | Chemistry |
| 收录类别 | SCI |
| 资助信息 | National Natural Science Foundation of China [41106138, 41206135]; MOST [2012AA092104, 2010CB833805]; CAS [XDA11030403, KSCX2-EW-G-12] |
| 原文出处 | PERGAMON-ELSEVIER SCIENCE LTD |
| WOS记录号 | WOS:000342711300029 |
| 公开日期 | 2014-12-11 |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/10370]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 推荐引用方式 GB/T 7714 | Zhou, X,Huang, HB,Li, J,et al. New anti-infective cycloheptadepsipeptide congeners and absolute stereochemistry from the deep sea-derived Streptomyces drozdowiczii SCSIO 10141[J]. TETRAHEDRON,2014,70(42):7795-7801. |
| APA | Zhou, X.,Huang, HB.,Li, J.,Song, YX.,Jiang, RW.,...&Ju, JH.(2014).New anti-infective cycloheptadepsipeptide congeners and absolute stereochemistry from the deep sea-derived Streptomyces drozdowiczii SCSIO 10141.TETRAHEDRON,70(42),7795-7801. |
| MLA | Zhou, X,et al."New anti-infective cycloheptadepsipeptide congeners and absolute stereochemistry from the deep sea-derived Streptomyces drozdowiczii SCSIO 10141".TETRAHEDRON 70.42(2014):7795-7801. |
入库方式： OAI收割
来源：南海海洋研究所
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