New phenyl derivatives from endophytic fungus Aspergillus flavipes AIL8 derived of mangrove plant Acanthus ilicifolius
文献类型：期刊论文
| 作者 | Bai, ZQ ; Lin, XP ; Wang, YZ ; Wang, JF ; Zhou, XF ; Yang, B ; Liu, J ; Yang, XW ; Wang, Y ; Liu, YH |
| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2014 |
| 卷号 | 95页码:194-202 |
| 关键词 | Butyrolactones Endophytic fungus Aspergillus flavipes Mangrove plant Acanthus ilicifolius |
| ISSN号 | 0367-326X |
| 通讯作者 | yonghongliu@scsio.ac.cn |
| 中文摘要 | Two new aromatic butyrolactones, flavipesins A (1) and B (2), two new natural products (3 and 4), and a known phenyl dioxolanone (5) were isolated from marine-derived endophytic fungus Aspergillus flavipes. The structures of compounds 1-5 were elucidated by 1D- and 2D-NMR and MS analysis, the absolute configurations were assigned by optical rotation and CD data, and the stereochemistry of 1 was determined by X-ray crystallography analysis. I demonstrated lower MIC values against Staphylococcus aureus (8.0 mu g/mL) and Bacillus subtillis (0.25 mu g/mL). I also showed the unique antibiofilm activity of penetration through the biofilm matrix and kills live bacteria inside mature S. aureus biofilm. (C) 2014 Elsevier B.V. All rights reserved. |
| 学科主题 | Pharmacology & Pharmacy |
| 收录类别 | SCI |
| 资助信息 | National Key Basic Research Program of China (973)'s Project [2010CB833800, 2011CB915503]; National High Technology Research and Development Program (863 Program) [2012AA092104]; National Natural Science Foundation of China [31270402, 21172230, 30973679, 41176148, 21002110]; Guangdong Province-CAS Joint Research Program [2011B090300023, 2012B091100264]; Guangdong Marine Economic Development and Innovation of Regional Demonstration Project [GD2012-D01-001, GD2012-D01-002] |
| 原文出处 | ELSEVIER SCIENCE BV |
| WOS记录号 | WOS:000336819400027 |
| 公开日期 | 2014-12-11 |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/10434]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 推荐引用方式 GB/T 7714 | Bai, ZQ,Lin, XP,Wang, YZ,et al. New phenyl derivatives from endophytic fungus Aspergillus flavipes AIL8 derived of mangrove plant Acanthus ilicifolius[J]. FITOTERAPIA,2014,95:194-202. |
| APA | Bai, ZQ.,Lin, XP.,Wang, YZ.,Wang, JF.,Zhou, XF.,...&Liu, YH.(2014).New phenyl derivatives from endophytic fungus Aspergillus flavipes AIL8 derived of mangrove plant Acanthus ilicifolius.FITOTERAPIA,95,194-202. |
| MLA | Bai, ZQ,et al."New phenyl derivatives from endophytic fungus Aspergillus flavipes AIL8 derived of mangrove plant Acanthus ilicifolius".FITOTERAPIA 95(2014):194-202. |
入库方式： OAI收割
来源：南海海洋研究所
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