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Tunable rigidity of (polymeric core)-(lipid shell) nanoparticles for regulated cellular uptake
文献类型：期刊论文
| 作者 | Sun JS(孙佳姝) ; Zhang L(张璐); Wang JL(王九令); Feng Q(冯强); Liu DB; Yin QF(殷其放); Xu DY; Wei YJ(魏宇杰); Ding BQ(丁宝全); Shi XH(施兴华)
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| 刊名 | Advanced Materials
 |
| 出版日期 | 2014-12-22 |
| 卷号 | 25期号:8页码:1402-1407 |
| 通讯作者邮箱 | shixh@imech.ac.cn ; xingyujiang@nanoctr.cn |
| 关键词 | microfluidics core–shell nanoparticles biomedical applications cellular uptake drug delivery |
| ISSN号 | 0935-9648 |
| 通讯作者 | 施兴华 |
| 合作状况 | 国内 |
| 中文摘要 | Core-shell nanoparticles (NPs) with lipid shells and varying water content and rigidity but with the same chemical composition, size, and surface properties are assembled using a microfluidic platform. Rigidity can dramatically alter the cellular uptake efficiency, with more-rigid NPs able to pass more easily through cell membranes. The mechanism accounting for this rigidity-dependent cellular uptake is revealed through atomistic-level simulations. |
| 学科主题 | 固体力学 ; 生物力学 |
| 分类号 | 一类 |
| 收录类别 | SCI ; EI |
| 原文出处 | http://onlinelibrary.wiley.com/doi/10.1002/adma.201404788/abstract |
| 语种 | 英语 |
| WOS记录号 | WOS:000350058200015 |
| 公开日期 | 2014-12-26 |
| 源URL | [http://dspace.imech.ac.cn/handle/311007/49407]  |
| 专题 | 力学研究所_非线性力学国家重点实验室 |
| 通讯作者 | Shi XH(施兴华); Shi XH(施兴华) |
| 推荐引用方式 GB/T 7714 | Sun JS,Zhang L,Wang JL,et al. Tunable rigidity of (polymeric core)-(lipid shell) nanoparticles for regulated cellular uptake[J]. Advanced Materials,2014,25(8):1402-1407. |
| APA | Sun JS.,Zhang L.,Wang JL.,Feng Q.,Liu DB.,...&施兴华.(2014).Tunable rigidity of (polymeric core)-(lipid shell) nanoparticles for regulated cellular uptake.Advanced Materials,25(8),1402-1407. |
| MLA | Sun JS,et al."Tunable rigidity of (polymeric core)-(lipid shell) nanoparticles for regulated cellular uptake".Advanced Materials 25.8(2014):1402-1407. |
入库方式： OAI收割
来源：力学研究所
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