Two new sesquiterpenes from Artemisia sieversiana
文献类型：期刊论文
| 作者 | Liu, Shi-Jun1,3; Liao, Zhi-Xin1,3; Liu, Chao1; Ji, Lan-Ju2; Sun, Hong-Fa2 |
| 刊名 | fitoterapia
 |
| 出版日期 | 2014-09-01 |
| 卷号 | 97页码:43-49 |
| 关键词 | Artemisia sieversiana Compositae Sesquiterpene Lignan Flavone Cytotoxic activity |
| ISSN号 | 0367-326x |
| 中文摘要 | two new sesquiterpenes, together with 32 known compounds(3-34), were isolated from artemisia sieversiana ehrhart ex willd. and the compounds 3-21 were isolated from this plant for the first time. the new compounds were elucidated as 2a,9a-dihydroxymuurol-3(4)-en-12-oic acid (1) and 13 alpha-methyl-(5 alpha h,6 alpha h,7 alpha h,8 alpha h)-austricin 8-o-beta-d-glucopyranoside (2), respectively. the structural identification of these compounds was mainly achieved by spectroscopic methods including 1d and 2d nmr techniques, and the structure of compound 1 was confirmed by a single crystal x-ray diffraction experiment. compounds 1-2 were evaluated for cytotoxic activity in vitro against mcf-7, nci-h460 and hep-g2 cell lines, respectively. (c) 2014 elsevier b.v. all rights reserved. |
| 英文摘要 | two new sesquiterpenes, together with 32 known compounds(3-34), were isolated from artemisia sieversiana ehrhart ex willd. and the compounds 3-21 were isolated from this plant for the first time. the new compounds were elucidated as 2a,9a-dihydroxymuurol-3(4)-en-12-oic acid (1) and 13 alpha-methyl-(5 alpha h,6 alpha h,7 alpha h,8 alpha h)-austricin 8-o-beta-d-glucopyranoside (2), respectively. the structural identification of these compounds was mainly achieved by spectroscopic methods including 1d and 2d nmr techniques, and the structure of compound 1 was confirmed by a single crystal x-ray diffraction experiment. compounds 1-2 were evaluated for cytotoxic activity in vitro against mcf-7, nci-h460 and hep-g2 cell lines, respectively. (c) 2014 elsevier b.v. all rights reserved. |
| WOS标题词 | science & technology ; life sciences & biomedicine |
| 类目[WOS] | chemistry, medicinal ; pharmacology & pharmacy |
| 研究领域[WOS] | pharmacology & pharmacy |
| 关键词[WOS] | cytotoxic activity ; constituents ; lactones ; leaves ; identification ; diterpenoids ; lignans ; tobacco ; bark |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000341346400006 |
| 公开日期 | 2014-12-19 |
| 源URL | [http://ir.nwipb.ac.cn/handle/363003/4194]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 作者单位 | 1.Southeast Univ, Dept Pharmaceut Engn, Sch Chem & Chem Engn, Nanjing 211189, Jiangsu, Peoples R China 2.Chinese Acad Sci, Northwest Inst Plateau Biol, Xining 810008, Peoples R China 3.Southeast Univ, Jiangsu Prov Hitech Key Lab Biomed Res, Nanjing 211189, Jiangsu, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Shi-Jun,Liao, Zhi-Xin,Liu, Chao,et al. Two new sesquiterpenes from Artemisia sieversiana[J]. fitoterapia,2014,97:43-49. |
| APA | Liu, Shi-Jun,Liao, Zhi-Xin,Liu, Chao,Ji, Lan-Ju,&Sun, Hong-Fa.(2014).Two new sesquiterpenes from Artemisia sieversiana.fitoterapia,97,43-49. |
| MLA | Liu, Shi-Jun,et al."Two new sesquiterpenes from Artemisia sieversiana".fitoterapia 97(2014):43-49. |
入库方式： OAI收割
来源：西北高原生物研究所
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