Cytotoxic diterpenoids from Salvia yunnanensis
文献类型：期刊论文
| 作者 | Wu, Chun-Yan1; Liao, Yang1; Yang, Zi-Gang1; Yang, Xing-Wei1 ; Shen, Xiao-Ling2; Li, Rong-Tao3; Xu, Gang1
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| 刊名 | PHYTOCHEMISTRY
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| 出版日期 | 2014-10-01 |
| 卷号 | 106页码:171-177 |
| 关键词 | Diterpenoids Salvia yunnanensis Lamiaceae Salyunnanins A-F Cytotoxicity |
| ISSN号 | 0031-9422 |
| 产权排序 | 第一 |
| 通讯作者 | Shen,XL (reprint author),Guangzhou Univ Chinese Med,Inst Trop Med,Lab Chinese Herbal Drug Discovery,Guangzhou 510405,Guangdong,Peoples R China. ; xlshen66@126.com ; lrt512@163.com ; xugang008@mail.kib.ac.cn |
| 英文摘要 | Forty-six abietane type diterpenoids possessing nine different fused ring systems were characterized from the roots of Salvia yunnanensis, six of which (salyunnanins A-F, 1-6) had different nor-abietane, homo-abietane, seco-abietane, and normal abietane architectures. Their structures were elucidated by comprehensive NMR and MS spectroscopic analyses. The inhibitory activities of these isolates against six human tumor lines were tested in vitro. Several of the compounds exhibited substantial cytotoxicity with IC50 values of 0.86-10.1 mu M. (C) 2014 Elsevier Ltd. All rights reserved. |
| 学科主题 | Biochemistry & Molecular Biology ; Plant Sciences |
| 类目[WOS] | Biochemistry & Molecular Biology ; Plant Sciences |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Plant Sciences |
| 关键词[WOS] | TUMOR-CELL-LINES ; ABIETANE DITERPENOIDS ; STRUCTURE ELUCIDATION ; BIOLOGICAL-ACTIVITIES ; NEO-TANSHINLACTONE ; ANTITUMOR AGENTS ; MILTIORRHIZA ; ROOTS ; PRZEWALSKII ; SKELETON |
| 收录类别 | SCI ; IC |
| 资助信息 | foundation from NSFC [81373291, 20702054]; CAS [KSCX2-EW-J-24]; SLAB [G102404]; Young Academic Leader Raising Foundation of Yunnan Province [2009CI073]; foundation from CAS |
| 语种 | 英语 |
| WOS记录号 | WOS:000342258600017 |
| 公开日期 | 2014-11-25 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/18381]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Guangzhou Univ Chinese Med, Inst Trop Med, Lab Chinese Herbal Drug Discovery, Guangzhou 510405, Guangdong, Peoples R China 3.Kunming Univ Sci & Technol, Fac Life Sci & Technol, Kunming 650050, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Chun-Yan,Liao, Yang,Yang, Zi-Gang,et al. Cytotoxic diterpenoids from Salvia yunnanensis[J]. PHYTOCHEMISTRY,2014,106:171-177. |
| APA | Wu, Chun-Yan.,Liao, Yang.,Yang, Zi-Gang.,Yang, Xing-Wei.,Shen, Xiao-Ling.,...&Xu, Gang.(2014).Cytotoxic diterpenoids from Salvia yunnanensis.PHYTOCHEMISTRY,106,171-177. |
| MLA | Wu, Chun-Yan,et al."Cytotoxic diterpenoids from Salvia yunnanensis".PHYTOCHEMISTRY 106(2014):171-177. |
入库方式： OAI收割
来源：昆明植物研究所
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