Cytotoxic eburnamine-aspidospermine type bisindole alkaloids from Bousigonia mekongensis
文献类型：期刊论文
| 作者 | Fu, Yan-hui1,2 ; Li, Shun-lin1; Li, Shi-fei1; He, Hong-ping1; Di, Ying-tong1; Zhang, Yu1; Hao, Xiao-jiang1
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| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2014-10-01 |
| 卷号 | 98页码:45-52 |
| ISSN号 | 0367-326X |
| 关键词 | Bousigonia mekongensis Bisindole alkaloids Mekongenines C-F Cytotoxicity |
| 通讯作者 | Zhang,Y (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China. ; zhangyu@mail.kib.ac.cn ; haoxj@mail.kib.ac.cn |
| 产权排序 | 第一 |
| 英文摘要 | Four new eburnamine-aspidospermine type bisindole alkaloids, namely, mekongenines C-F (1-4), along with 27 known indole alkaloids were isolated from the twigs and leaves of Bousigonia mekongensis. Their structures with the absolute configurations were elucidated by spectroscopic methods and ECD analyses. All new compounds were evaluated for their cytotoxicities against five human cancer cell lines: HL-60, SMMC-7721, A-549, MCF-7 and SW480 in vitro. Alkaloids 1-4 exhibited inhibitory effects with IC50 values comparable to those of cisplatin. (C) 2014 Elsevier B.V. All rights reserved. |
| 学科主题 | Pharmacology & Pharmacy |
| 类目[WOS] | Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Pharmacology & Pharmacy |
| 关键词[WOS] | MELODINUS-SCANDENS FORST ; VINCA ALKALOIDS ; NEW-CALEDONIA ; PLANTS ; VINCARODINE ; VINDOLININE |
| 资助信息 | National Natural Science Foundation of China [31100259, 21302181] |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000343617600006 |
| 公开日期 | 2014-11-25 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/18403]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Hainan Normal Univ, Key Lab Trop Med Plant Chem, Minist Educ, Haikou 571158, Peoples R China |
| 推荐引用方式 GB/T 7714 | Fu, Yan-hui,Li, Shun-lin,Li, Shi-fei,et al. Cytotoxic eburnamine-aspidospermine type bisindole alkaloids from Bousigonia mekongensis[J]. FITOTERAPIA,2014,98:45-52. |
| APA | Fu, Yan-hui.,Li, Shun-lin.,Li, Shi-fei.,He, Hong-ping.,Di, Ying-tong.,...&Hao, Xiao-jiang.(2014).Cytotoxic eburnamine-aspidospermine type bisindole alkaloids from Bousigonia mekongensis.FITOTERAPIA,98,45-52. |
| MLA | Fu, Yan-hui,et al."Cytotoxic eburnamine-aspidospermine type bisindole alkaloids from Bousigonia mekongensis".FITOTERAPIA 98(2014):45-52. |
入库方式： OAI收割
来源：昆明植物研究所
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