Joint detection of tumor markers with imaging ellipsometry biosensor
文献类型：期刊论文
| 作者 | Niu Y(牛宇) ; Kang TF(康腾飞); Jin G(靳刚)
|
| 刊名 | Thin Solid Films
 |
| 出版日期 | 2014-11-28 |
| 卷号 | 571页码:453-462 |
| 通讯作者邮箱 | gajin@imech.ac.cn |
| 关键词 | Joint detection Tumor markers Biosensor Imaging ellipsometry |
| ISSN号 | 0040-6090 |
| 产权排序 | [Niu, Yu; Kang, Tengfei; Jin, Gang] Chinese Acad Sci, Inst Mech, NML, Beijing 100190, Peoples R China; [Kang, Tengfei] Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 通讯作者 | Jin, G (reprint author), 15 Bei Si Huan West Rd, Beijing 100190, Peoples R China. |
| 合作状况 | 国内 |
| 中文摘要 | Tumor marker detection contributes to the early diagnosis of cancers. However, due to the lack of detection specificity, its results cannot act as a direct evidence to confirm cancer occurrence in clinic. Joint detection of tumor markers may improve the detection specificity. As a trial for clinical diagnosis of hepatocellular carcinoma, alpha-fetoprotein, alpha-L-fucosidase and ferritin have been combined and detected with a label-free, phase sensitive and high throughput imaging ellipsometry biosensor (IEB). Eighty-two sera have been quantitatively detected with IEB and the results are in agreement with the clinical standard approaches. Evaluated by receiver operating characteristic analysis, the specificity of joint detection improves remarkably with IEB for hepatocellular carcinoma. It can be foreseen that the joint detection of tumor markers with IEB has a potential for clinical cancer diagnosis. (C) 2014 Elsevier B.V. All rights reserved. |
| 学科主题 | Materials Science ; Physics |
| 分类号 | 二类/Q2 |
| 类目[WOS] | Materials Science, Multidisciplinary ; Materials Science, Coatings & Films ; Physics, Applied ; Physics, Condensed Matter |
| 研究领域[WOS] | Materials Science ; Physics |
| 关键词[WOS] | CANCER ; VISUALIZATION |
| 收录类别 | SCI ; EI |
| 原文出处 | http://dx.doi.org/10.1016/j.tsf.2014.01.043 |
| 语种 | 英语 |
| WOS记录号 | WOS:000346055200021 |
| 公开日期 | 2015-01-23 |
| 源URL | [http://dspace.imech.ac.cn/handle/311007/49491]  |
| 专题 | 力学研究所_国家微重力实验室 |
| 推荐引用方式 GB/T 7714 | Niu Y,Kang TF,Jin G. Joint detection of tumor markers with imaging ellipsometry biosensor[J]. Thin Solid Films,2014,571:453-462. |
| APA | Niu Y,Kang TF,&Jin G.(2014).Joint detection of tumor markers with imaging ellipsometry biosensor.Thin Solid Films,571,453-462. |
| MLA | Niu Y,et al."Joint detection of tumor markers with imaging ellipsometry biosensor".Thin Solid Films 571(2014):453-462. |
入库方式： OAI收割
来源：力学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。