New Sinularianin Sesquiterpenes from Soft Coral Sinularia sp.
文献类型：期刊论文
| 作者 | [Yang, Bin ; Liao, Shengrong ; Lin, Xiuping ; Wang, Junfeng ; Liu, Juan ; Zhou, Xuefeng ; Yang, Xianwen ; Liu, Yonghong] Chinese Acad Sci, South China Sea Inst Oceanol, Res Ctr Marine Microbes, CAS Key Lab Trop Marine Bioresources & Ecol,Guang, Guangzhou 510301, Guangdong, Peoples R China |
| 刊名 | MARINE DRUGS
 |
| 出版日期 | 2013 |
| 卷号 | 11期号:12页码:4741-4750 |
| 关键词 | soft coral Sinularia sp sesquiterpenes sinularianins NF-B |
| ISSN号 | 1660-3397 |
| 通讯作者 | bingo525@163.com ; ljrss@126.com ; xiupinglin@hotmail.com ; junfeng1982a@163.com ; ljuan2010@qq.com ; xfzhou@scsio.ac.cn ; xwyang@scsio.ac.cn ; yonghongliu@scsio.ac.cn |
| 中文摘要 | Four new sesquiterpenes, sinularianins C-F (3-6), together with known sinularianins A (1) and B (2) were identified from a South China Sea soft coral Sinularia sp. Compounds 1-6 were evaluated for inhibition of NF-B activation using the cell-based HEK293 NF-B luciferase reporter gene assay. Compounds 1 and 4 were exhibited a potent effect with inhibitory rates of 41.3% and 43.0% at the concentration of 10 mu g/mL, respectively. |
| 学科主题 | Chemistry, Medicinal |
| 资助信息 | This study was supported by grants from the National Key Basic Research Program of China (973)'s Project (2010CB833800 and 2011CB915503), the National High Technology Research and Development Program (863 Program, 2012AA092104), National Natural Science Foundation of China (21302198, 31270402, 21172230, 30973679, 41376162 and 41176148), Knowledge Innovation Program of Chinese Academy of Science (SQ201117 and SQ201019), Guangdong Province-CAS Joint Research Program (2011B090300023 and 2012B091100264), and Guangdong Marine Economic Development and Innovation of Regional Demonstration Project (GD2012-D01-001 and GD2012-D01-002). |
| 原文出处 | MDPI AG |
| 语种 | 英语 |
| WOS记录号 | WOS:000330220400003 |
| 公开日期 | 2015-01-22 |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/10952]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 推荐引用方式 GB/T 7714 | [Yang, Bin,Liao, Shengrong,Lin, Xiuping,et al. New Sinularianin Sesquiterpenes from Soft Coral Sinularia sp.[J]. MARINE DRUGS,2013,11(12):4741-4750. |
| APA | [Yang, Bin.,Liao, Shengrong.,Lin, Xiuping.,Wang, Junfeng.,Liu, Juan.,...&Liu, Yonghong] Chinese Acad Sci, South China Sea Inst Oceanol, Res Ctr Marine Microbes, CAS Key Lab Trop Marine Bioresources & Ecol,Guang, Guangzhou 510301, Guangdong, Peoples R China.(2013).New Sinularianin Sesquiterpenes from Soft Coral Sinularia sp..MARINE DRUGS,11(12),4741-4750. |
| MLA | [Yang, Bin,et al."New Sinularianin Sesquiterpenes from Soft Coral Sinularia sp.".MARINE DRUGS 11.12(2013):4741-4750. |
入库方式： OAI收割
来源：南海海洋研究所
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