中国科学院机构知识库网格系统: Four New 7,8-Epoxycembranoids from a Chinese Soft Coral Lobophytum sp.

Four New 7,8-Epoxycembranoids from a Chinese Soft Coral Lobophytum sp.

文献类型：期刊论文


作者	[Zhao, Min ; Zhao, Feng ; Cheng, Shimiao ; Xiang, Zheng ; Dong, Jianyong ; Huang, Kexin ; Yan, Pengcheng] Wenzhou Med Univ, Sch Pharm, Wenzhou 325035, Zhejiang, Peoples R China ; [Li, Xiubao] Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China
刊名	CHEMICAL & PHARMACEUTICAL BULLETIN
出版日期	2013
卷号	61 期号:12 页码:1323-1328
关键词	soft coral Lobophytum 7 nitric oxide (NO) inhibition 8-epoxycembranoid
ISSN号	0009-2363
通讯作者	xzh007@126.com ; yanpc@wzmc.edu.cn
中文摘要	Four new 7,8-epoxycembranoids, namely (2S,7S,8S,12R,1Z,3E,10E)-7,8:2,16-diepoxycembra-1(15), 3,10-trien-12-ol (1), (2S,7S,8S,11R,1Z,3E)-7,8:2,16-diepoxycembra-1(15),3,12(20)-trien-11-ol (2), (4S, 7S,8S,1Z,2E,11E)-16-acetoxy-7,8-epoxycembra-1(15),2,11-trien-4-ol (3), and (7S,8S,15S,1E,3E,11E)-7,8-epoxycembra-1,3,11-trien-15,16-diol (4) were isolated from a Chinese soft coral Lobophytum sp., together with eleven known analogues 5-15. The structures of the new compounds were determined by extensive spectroscopic data analysis. All compounds were tested for the inhibitory effect on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in mouse peritoneal macrophages (PEM Phi).
学科主题	Chemistry, Medicinal ; Chemistry, Multidisciplinary ; Pharmacology & Pharmacy
资助信息	This research was supported by Grant from the NSFC (No. 21202123) and Start-Up Funding from Wenzhou Medical University (No. QTJ10018).
原文出处	PHARMACEUTICAL SOC JAPAN
语种	英语
WOS记录号	WOS:000327573700016
公开日期	2015-01-22
源URL	[http://ir.scsio.ac.cn/handle/344004/10957]
专题	南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
推荐引用方式 GB/T 7714	[Zhao, Min,Zhao, Feng,Cheng, Shimiao,et al. Four New 7,8-Epoxycembranoids from a Chinese Soft Coral Lobophytum sp.[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2013,61(12):1323-1328.
APA	[Zhao, Min.,Zhao, Feng.,Cheng, Shimiao.,Xiang, Zheng.,Dong, Jianyong.,...&[Li, Xiubao] Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China.(2013).Four New 7,8-Epoxycembranoids from a Chinese Soft Coral Lobophytum sp..CHEMICAL & PHARMACEUTICAL BULLETIN,61(12),1323-1328.
MLA	[Zhao, Min,et al."Four New 7,8-Epoxycembranoids from a Chinese Soft Coral Lobophytum sp.".CHEMICAL & PHARMACEUTICAL BULLETIN 61.12(2013):1323-1328.

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来源：南海海洋研究所

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Four New 7,8-Epoxycembranoids from a Chinese Soft Coral Lobophytum sp.

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