中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Two New Compounds from Gorgonian-associated Fungus Aspergillus sp.

文献类型:期刊论文

作者[Xu, Xin-Ya ; Zhang, Xiao-Yong ; He, Fei ; Peng, Jiang ; Nong, Xu-Hua ; Qi, Shu-Hua] Chinese Acad Sci, Key Lab Marine Bioresources Sustainable Utilizat, Guangdong Key Lab Marine Mat Med, South China Sea Inst Oceanol, Guangzhou 510301, Guangdong, Peoples R China ; [Peng, Jiang ; Nong, Xu-Hua] Univ Chinese Acad Sci, Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
刊名NATURAL PRODUCT COMMUNICATIONS
出版日期2013
卷号8期号:8页码:1069-1070
关键词Gorgonian-associated fungus Aspergillus sp. gamma-Lactone Lactam
ISSN号1934-578X
通讯作者shuhuaqi@scsio.ac.cn
中文摘要One new gamma-lactone derivative 5-hydroxy-3-isopropyl-4-methoxyfuranone (1) and one new lactam derivative dehydrated-marinamide (2), along with two known compounds marinamide (3) and marinamide methyl ester (4) were isolated from the fermentation broth of the marine gorgonian-associated fungus Aspergillus sp. SCSGAF0093. Their structures were elucidated on the basis of spectroscopic and spectrometric analysis. Compound 1 showed significant toxicity to brine shrimp (Artemia sauna) with a median lethal concentration (LC50) of 1.25 mu M, and 3 inhibited protein tyrosine phosphatase 1B (PTPIB) with a half maximal inhibitory concentration (IC50) of 23.3 mu g/mL.
学科主题Chemistry, Medicinal ; Food Science & Technology
资助信息The authors are grateful to 973 Program of China (2010CB833803), 863 Program of China (2012AA092104), National Marine Public Welfare Research Project of China (grant 201305017), and National Natural Science Foundation of China (40931160435 and 40976090) for financial support.
原文出处NATURAL PRODUCTS INC
语种英语
WOS记录号WOS:000323687500007
公开日期2015-01-22
源URL[http://ir.scsio.ac.cn/handle/344004/11000]  
专题南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
推荐引用方式
GB/T 7714
[Xu, Xin-Ya,Zhang, Xiao-Yong,He, Fei,et al. Two New Compounds from Gorgonian-associated Fungus Aspergillus sp.[J]. NATURAL PRODUCT COMMUNICATIONS,2013,8(8):1069-1070.
APA [Xu, Xin-Ya.,Zhang, Xiao-Yong.,He, Fei.,Peng, Jiang.,Nong, Xu-Hua.,...&Nong, Xu-Hua] Univ Chinese Acad Sci, Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China.(2013).Two New Compounds from Gorgonian-associated Fungus Aspergillus sp..NATURAL PRODUCT COMMUNICATIONS,8(8),1069-1070.
MLA [Xu, Xin-Ya,et al."Two New Compounds from Gorgonian-associated Fungus Aspergillus sp.".NATURAL PRODUCT COMMUNICATIONS 8.8(2013):1069-1070.

入库方式: OAI收割

来源:南海海洋研究所

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