Two New Compounds from Gorgonian-associated Fungus Aspergillus sp.
文献类型:期刊论文
作者 | [Xu, Xin-Ya ; Zhang, Xiao-Yong ; He, Fei ; Peng, Jiang ; Nong, Xu-Hua ; Qi, Shu-Hua] Chinese Acad Sci, Key Lab Marine Bioresources Sustainable Utilizat, Guangdong Key Lab Marine Mat Med, South China Sea Inst Oceanol, Guangzhou 510301, Guangdong, Peoples R China ; [Peng, Jiang ; Nong, Xu-Hua] Univ Chinese Acad Sci, Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
刊名 | NATURAL PRODUCT COMMUNICATIONS
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出版日期 | 2013 |
卷号 | 8期号:8页码:1069-1070 |
关键词 | Gorgonian-associated fungus Aspergillus sp. gamma-Lactone Lactam |
ISSN号 | 1934-578X |
通讯作者 | shuhuaqi@scsio.ac.cn |
中文摘要 | One new gamma-lactone derivative 5-hydroxy-3-isopropyl-4-methoxyfuranone (1) and one new lactam derivative dehydrated-marinamide (2), along with two known compounds marinamide (3) and marinamide methyl ester (4) were isolated from the fermentation broth of the marine gorgonian-associated fungus Aspergillus sp. SCSGAF0093. Their structures were elucidated on the basis of spectroscopic and spectrometric analysis. Compound 1 showed significant toxicity to brine shrimp (Artemia sauna) with a median lethal concentration (LC50) of 1.25 mu M, and 3 inhibited protein tyrosine phosphatase 1B (PTPIB) with a half maximal inhibitory concentration (IC50) of 23.3 mu g/mL. |
学科主题 | Chemistry, Medicinal ; Food Science & Technology |
资助信息 | The authors are grateful to 973 Program of China (2010CB833803), 863 Program of China (2012AA092104), National Marine Public Welfare Research Project of China (grant 201305017), and National Natural Science Foundation of China (40931160435 and 40976090) for financial support. |
原文出处 | NATURAL PRODUCTS INC |
语种 | 英语 |
WOS记录号 | WOS:000323687500007 |
公开日期 | 2015-01-22 |
源URL | [http://ir.scsio.ac.cn/handle/344004/11000] ![]() |
专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
推荐引用方式 GB/T 7714 | [Xu, Xin-Ya,Zhang, Xiao-Yong,He, Fei,et al. Two New Compounds from Gorgonian-associated Fungus Aspergillus sp.[J]. NATURAL PRODUCT COMMUNICATIONS,2013,8(8):1069-1070. |
APA | [Xu, Xin-Ya.,Zhang, Xiao-Yong.,He, Fei.,Peng, Jiang.,Nong, Xu-Hua.,...&Nong, Xu-Hua] Univ Chinese Acad Sci, Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China.(2013).Two New Compounds from Gorgonian-associated Fungus Aspergillus sp..NATURAL PRODUCT COMMUNICATIONS,8(8),1069-1070. |
MLA | [Xu, Xin-Ya,et al."Two New Compounds from Gorgonian-associated Fungus Aspergillus sp.".NATURAL PRODUCT COMMUNICATIONS 8.8(2013):1069-1070. |
入库方式: OAI收割
来源:南海海洋研究所
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