Thaixylomolins A-C: Limonoids Featuring Two New Motifs from the Thai Xylocarpus moluccensis
文献类型：期刊论文
| 作者 | [Li, Jun] Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China ; [Li, Min-Yi ; Wu, Jun] Jinan Univ, Coll Pharm, Marine Drugs Res Ctr, Guangzhou 510632, Guangdong, Peoples R China ; [Bruhn, Torsten ; Katele, Felix Zongwe ; Bringmann, Gerhard] Univ Wurzburg, Inst Organ Chem, D-97074 Wurzburg, Germany ; [Xiao, Qiang] Jiangxi Sci & Technol Normal Univ, Inst Organ Chem, Nanchang 330013, Peoples R China ; [Pedpradab, Patchara] Rajamangala Univ Technol Srivijaya, Dept Marine Sci, Fac Sci & Fishery Technol, Songkhla 92150, Trang Province, Thailand ; [Li, Jun] Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2013 |
| 卷号 | 15期号:14页码:3682-3685 |
| ISSN号 | 1523-7060 |
| 通讯作者 | wwujun2003@yahoo.com ; bringmann@chemie.uni-wuerzburg.de |
| 中文摘要 | Three limonoids named thaixylomolins A-C (1-3), featuring two new motifs, were isolated from the seeds of a Thai mangrove, Xylocarpus moluccensis. The absolute configurations of these limonoids were determined by extensive NMR investigations, single-crystal X-ray diffraction analysis, and circular-dichroism spectroscopy in combination with quantum-chemical calculations. Thaixylomolin B exhibited inhibitory activity against nitric oxide production in lipopolysaccharide and IFN-gamma-induced RAW264.7 murine macrophages with an IC50 value of 84.3 mu M. |
| 学科主题 | Chemistry, Organic |
| 资助信息 | This work was supported by NSFC (31100258, 31170331, and 81125022), the Guangdong Key Science and Technology Special Project (2011A080403020), and the Deutsche Forschungsge-meinschaft (SFB 630, "Recognition, Preparation, and Functional Analysis of Agents against Infectious Diseases"). F.Z.K. is grateful to the BEBUC Scholarship System for a fellowship. |
| 原文出处 | AMER CHEMICAL SOC |
| 语种 | 英语 |
| WOS记录号 | WOS:000322210600050 |
| 公开日期 | 2015-01-22 |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/11007]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 推荐引用方式 GB/T 7714 | [Li, Jun] Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China,[Li, Min-Yi,Wu, Jun] Jinan Univ, Coll Pharm, Marine Drugs Res Ctr, Guangzhou 510632, Guangdong, Peoples R China,et al. Thaixylomolins A-C: Limonoids Featuring Two New Motifs from the Thai Xylocarpus moluccensis[J]. ORGANIC LETTERS,2013,15(14):3682-3685. |
| APA | [Li, Jun] Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China.,[Li, Min-Yi.,Wu, Jun] Jinan Univ, Coll Pharm, Marine Drugs Res Ctr, Guangzhou 510632, Guangdong, Peoples R China.,[Bruhn, Torsten.,Katele, Felix Zongwe.,...&[Li, Jun] Univ Chinese Acad Sci, Beijing 100049, Peoples R China.(2013).Thaixylomolins A-C: Limonoids Featuring Two New Motifs from the Thai Xylocarpus moluccensis.ORGANIC LETTERS,15(14),3682-3685. |
| MLA | [Li, Jun] Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China,et al."Thaixylomolins A-C: Limonoids Featuring Two New Motifs from the Thai Xylocarpus moluccensis".ORGANIC LETTERS 15.14(2013):3682-3685. |
入库方式： OAI收割
来源：南海海洋研究所
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