New mycotoxins from marine-derived fungus Aspergillus sp SCSGAF0093
文献类型:期刊论文
作者 | [Xu, Xinya ; He, Fei ; Zhang, Xiaoyong ; Bao, Jie ; Qi, Shuhua] Chinese Acad Sci, South China Sea Inst Oceanol, Guangdong Key Lab Marine Mat Med, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China ; [Bao, Jie] Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
刊名 | FOOD AND CHEMICAL TOXICOLOGY
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出版日期 | 2013 |
卷号 | 53页码:46-51 |
关键词 | Marine-derived fungus Aspergillus sp. Mycotoxins Aspergillic acid group Ochratoxins Brine shrimp toxicity |
ISSN号 | 0278-6915 |
通讯作者 | shuhuaqi@scsio.ac.cn |
中文摘要 | Nine mycotoxins including six aspergillic acid group toxins, aluminiumneoaspergillin (1), zirconiumneoaspergillin (2), aspergilliamide (3), ferrineoaspergillin (5), flavacol (6), neoaspergillic acid (7), and three ochratoxins, ochratoxin A n-butyl ester (4), ochratoxin A (8), ochratoxin A methyl ester (9), were isolated from the fermentation broth of marine gorgonian derived fungus Aspergillus sp. SCSGAF0093. Four of them (1-4) were new mycotoxins, and their structures were elucidated on the basis of spectroscopic analysis and chemical evidence. The bio-toxicity of compounds 1-9 were determined by brine shrimp lethality bioassay with median lethal concentration (LC50) values of 2.59-205.67 mu M. This was the first report about zirconium complex obtained from nature and ochratoxins isolated from marine environment. (c) 2012 Elsevier Ltd. All rights reserved. |
学科主题 | Food Science & Technology ; Toxicology |
资助信息 | The authors are grateful to the National Basic Research Program of China (973 Program, 2010CB833803), National High Technology Research and Development Program of China (863 Program, 2012AA092104), the National Natural Science Foundation of China (Grants 40931160435 and 40976090), and the Knowledge Innovation Program of Chinese Academy of Science (KSCX2-EW-G-12B) for financial support. |
原文出处 | PERGAMON-ELSEVIER SCIENCE LTD |
语种 | 英语 |
WOS记录号 | WOS:000322924700008 |
公开日期 | 2015-01-22 |
源URL | [http://ir.scsio.ac.cn/handle/344004/11055] ![]() |
专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
推荐引用方式 GB/T 7714 | [Xu, Xinya,He, Fei,Zhang, Xiaoyong,et al. New mycotoxins from marine-derived fungus Aspergillus sp SCSGAF0093[J]. FOOD AND CHEMICAL TOXICOLOGY,2013,53:46-51. |
APA | [Xu, Xinya,He, Fei,Zhang, Xiaoyong,Bao, Jie,Qi, Shuhua] Chinese Acad Sci, South China Sea Inst Oceanol, Guangdong Key Lab Marine Mat Med, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China,&[Bao, Jie] Univ Chinese Acad Sci, Beijing 100049, Peoples R China.(2013).New mycotoxins from marine-derived fungus Aspergillus sp SCSGAF0093.FOOD AND CHEMICAL TOXICOLOGY,53,46-51. |
MLA | [Xu, Xinya,et al."New mycotoxins from marine-derived fungus Aspergillus sp SCSGAF0093".FOOD AND CHEMICAL TOXICOLOGY 53(2013):46-51. |
入库方式: OAI收割
来源:南海海洋研究所
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