Endocrinology: Advances through omics and related technologies
文献类型：期刊论文
| 作者 | Garcia-Reyero, Natalia1; Tingaud-Sequeira, Angele2; Cao, Mengxi3,4; Zhu, Zuoyan3; Perkins, Edward J.5; Hu, Wei3 |
| 刊名 | GENERAL AND COMPARATIVE ENDOCRINOLOGY
 |
| 出版日期 | 2014-07-01 |
| 卷号 | 203期号:-页码:262-273 |
| 关键词 | Omics Reproduction Transgenic organisms Integrative systems biology |
| ISSN号 | 0016-6480 |
| 英文摘要 | The rapid development of new omics technologies to measure changes at genetic, transcriptomic, proteomic, and metabolomics levels together with the evolution of methods to analyze and integrate the data at a systems level are revolutionizing the study of biological processes. Here we discuss how new approaches using omics technologies have expanded our knowledge especially in nontraditional models. Our increasing knowledge of these interactions and evolutionary pathway conservation facilitates the use of nontraditional species, both invertebrate and vertebrate, as new model species for biological and endocrinology research. The increasing availability of technology to create organisms overexpressing key genes in endocrine function allows manipulation of complex regulatory networks such as growth hormone (GH) in transgenic fish where disregulation of GH production to produce larger fish has also permitted exploration of the role that GH plays in testis development, suggesting that it does so through interactions with insulin-like growth factors. The availability of omics tools to monitor changes at nearly any level in any organism, manipulate gene expression and behavior, and integrate data across biological levels, provides novel opportunities to explore endocrine function across many species and understand the complex roles that key genes play in different aspects of the endocrine function. (C) 2014 Elsevier Inc. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Endocrinology & Metabolism |
| 研究领域[WOS] | Endocrinology & Metabolism |
| 关键词[WOS] | ZEBRAFISH DANIO-RERIO ; SALMON ONCORHYNCHUS-KISUTCH ; MINNOWS PIMEPHALES-PROMELAS ; GROWTH-HORMONE SYNTHESIS ; PITUITARY-GONADAL AXIS ; GENE-EXPRESSION ; DAPHNIA-MAGNA ; MESSENGER-RNA ; SYSTEMS BIOLOGY ; RAINBOW-TROUT |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000341073300029 |
| 公开日期 | 2015-01-20 |
| 源URL | [http://ir.ihb.ac.cn/handle/342005/20350]  |
| 专题 | 水生生物研究所_鱼类生物学及渔业生物技术研究中心_期刊论文 |
| 作者单位 | 1.Mississippi State Univ, Inst Genom Biocomp & Biotechnol, Starkville, MS 39759 USA 2.Univ Bordeaux, Lab MRMG, F-33405 Talence, France 3.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 5.US Army Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA |
| 推荐引用方式 GB/T 7714 | Garcia-Reyero, Natalia,Tingaud-Sequeira, Angele,Cao, Mengxi,et al. Endocrinology: Advances through omics and related technologies[J]. GENERAL AND COMPARATIVE ENDOCRINOLOGY,2014,203(-):262-273. |
| APA | Garcia-Reyero, Natalia,Tingaud-Sequeira, Angele,Cao, Mengxi,Zhu, Zuoyan,Perkins, Edward J.,&Hu, Wei.(2014).Endocrinology: Advances through omics and related technologies.GENERAL AND COMPARATIVE ENDOCRINOLOGY,203(-),262-273. |
| MLA | Garcia-Reyero, Natalia,et al."Endocrinology: Advances through omics and related technologies".GENERAL AND COMPARATIVE ENDOCRINOLOGY 203.-(2014):262-273. |
入库方式： OAI收割
来源：水生生物研究所
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